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Combined effects of iontophoretic and chemical enhancement on drug delivery. II. Transport across human and murine skin.
- L. Nolan, J. Corish, O. Corrigan, D. Fitzpatrick
- Chemistry, Medicine
- International journal of pharmaceutics
- 16 August 2007
This paper reports measurements of the release characteristics of the model drug salbutamol from a liquid crystalline vehicle across both human and hairless murine skin in vitro. The use of oleic… Expand
Modelling skin permeability in risk assessment--the future.
The modelling of skin permeability is important for transdermal drug delivery, in the cosmetic industry and for risk assessment attendant on dermal exposure to toxic substances. The two principal… Expand
Analysis, interpretation, and extrapolation of dermal permeation data using diffusion-based mathematical models.
- J. Krüse, Darach Golden, Simon Wilkinson, F. Williams, S. Kezic, J. Corish
- Materials Science, Medicine
- Journal of pharmaceutical sciences
- 1 March 2007
New dermal penetration data have been measured in both "infinite" and finite dose experiments on a range of compounds of varying lipophilicities. The data are analyzed, using parameter fitting, to… Expand
The release of nicotine from a hydrogel containing ion exchange resins
Parameters influencing the release rates of nicotine from a range of agar-based gel vehicles containing ion exchange resins to which the nicotine had been bound have been determined. Measurements… Expand
Defect aggregation in anion-excess fluorites. Dopant monomers and dimers
A calculation of the Frenkel defect formation energy in silver chloride
A theoretical study has been made of the defect structure of silver chloride. An interionic potential based on the quasiharmonic model is developed and temperature-dependent Frenkel defect formation… Expand
Definitions of Terms for Diffusion in the Solid State
Synopsis: This document provides definitions of terms and processes which are used in describing the migration of host and foreign species through solid materials. Both the phenomenological theory of… Expand
An Atomistic Investigation of Helical Polythiophene
Abstract An atomistic lattice simulation method invoking bonded, nonbonded and torsional interactions has been used to simulate infinitely long polythiophene helices both as single chains and in a… Expand
A theoretical study of vacancy-impurity association and of defect aggregation processes in divalently-doped silver halide crystals
Abstract Defect structures in AgCl and AgBr doped with Zn2+, Mn2+, Cd2+, Sr2+ and Pb2+ have been investigated using computer simulation methods, and the forces between the ions have been described… Expand