In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS
In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide is investigated, using rats treated with intratracheal instillation of LPS as a model for ARDS.
Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis.
Pharmacokinetics, interactions with macromolecules and species differences in metabolism of DEHP.
- P. Albro, J. Corbett, J. Schroeder, S. Jordan, H. Matthews
- Biology, ChemistryEnvironmental Health Perspectives
- 1 November 1982
Radioactivity from carbonyl-labeled DEHP did not associate with purified protein, RNA or DNA from rat liver in vivo, and the apparent binding from DEHP and MEHP was not exchangeable, but was not proven to be covalent.
Application of the thiobarbiturate assay to the measurement of lipid peroxidation products in microsomes.
Activation of nonspecific lipase (EC 3.1.1.-) by bile salts.
P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice.
Lipids of the earthworm Lumbricus terrestris.
The lipid composition of the earthworm Lumbricus terrestris has been reexamined under conditions intended to avoid enzymatic and chemical alterations during storage, extraction, and fractionation procedures, and it is concluded that these acids were synthesized in the worms.
The Fate of the Oxidizing Tyrosyl Radical in the Presence of Glutathione and Ascorbate
- B. Sturgeon, H. J. Sipe, D. Barr, J. Corbett, J. G. Martínez, R. Mason
- Chemistry, BiologyJournal of Biological Chemistry
- 13 November 1998
Results indicate that in the presence of physiological concentrations of ascorbate and GSH, GSH is not involved in the detoxification pathway of oxidizing free radicals formed by peroxidases.
Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice.