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Advanced heart failure treated with continuous-flow left ventricular assist device.
TLDR
Treatment with a continuous-flow left ventricular assist device in patients with advanced heart failure significantly improved the probability of survival free from stroke and device failure at 2 years as compared with a pulsatile device. Expand
Transcatheter aortic-valve replacement with a self-expanding prosthesis.
TLDR
In patients with severe aortic stenosis who are at increased surgical risk, TAVR with a self-expanding transcatheter aorti-valve bioprosthesis was associated with a significantly higher rate of survival at 1 year than surgical aorticsvalve replacement. Expand
Use of a continuous-flow device in patients awaiting heart transplantation.
TLDR
A continuous-flow left ventricular assist device can provide effective hemodynamic support for a period of at least 6 months in patients awaiting heart transplantation, with improved functional status and quality of life. Expand
Surgical or Transcatheter Aortic‐Valve Replacement in Intermediate‐Risk Patients
TLDR
TAVR was a noninferior alternative to surgery in patients with severe aortic stenosis at intermediate surgical risk, with a different pattern of adverse events associated with each procedure. Expand
Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery.
TLDR
TAVR with a self-expanding bioprosthesis was safe and effective in patients with symptomatic severe aortic stenosis at prohibitive risk for surgical valve replacement. Expand
Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device.
TLDR
A continuous-flow LVAD provides effective hemodynamic support for at least 18 months in patients awaiting transplantation, with improved functional status and quality of life. Expand
International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung
TLDR
The transplant evaluation rating scale: a revision of the psychosocial levels system for evaluating organ transplant candidates and the influence of posttransplantation psychossocial factors on heart transplantation outcome are reviewed. Expand
Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension.
TLDR
The data suggest that defects in PASMC KV channels in PPH patients may be a unique mechanism involved in initiating and maintaining pulmonary vasoconstriction and appear to play a role in the pathogenesis of PPH. Expand
Working formulation for the standardization of definitions of infections in patients using ventricular assist devices.
TLDR
These standard definitions of infections in VAD patients are created by adapting and expanding on existing standardized definitions, which are based on the pathophysiology of equivalent infectious processes in prosthetic devices, such as cardiac prosthetic valve infections, intravascular catheter-related infections, and prosthetic joint infections. Expand
2-Year Outcomes in Patients Undergoing Surgical or Self-Expanding Transcatheter Aortic Valve Replacement.
TLDR
In patients with severe aortic stenosis who are at increased surgical risk, the higher rate of survival with a self-expanding TAVR compared with surgery was sustained at 2 years. Expand
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