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Bicuspid Aortic Cusp Fusion Morphology Alters Aortic Three-Dimensional Outflow Patterns, Wall Shear Stress, and Expression of Aortopathy
Background— Aortic 3-dimensional blood flow was analyzed to investigate altered ascending aorta (AAo) hemodynamics in bicuspid aortic valve (BAV) patients and its association with differences in cusp… Expand
Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy: Insights From Wall Shear Stress Mapping.
- David G. Guzzardi, A. Barker, +14 authors Paul W. M. Fedak
- Journal of the American College of Cardiology
- 25 August 2015
BACKGROUND Suspected genetic causes for extracellular matrix (ECM) dysregulation in the ascending aorta in patients with bicuspid aortic valves (BAV) have influenced strategies and thresholds for… Expand
Cardiac Magnetic Resonance T2 Mapping in the Monitoring and Follow-up of Acute Cardiac Transplant Rejection: A Pilot Study
Background—Acute rejection is a major factor impacting survival in the first 12 months after cardiac transplantation. Transplant monitoring requires invasive techniques. Cardiac magnetic resonance… Expand
Evaluation of peripheral arterial disease with nonenhanced quiescent-interval single-shot MR angiography.
PURPOSE To assess the diagnostic performance of quiescent-interval single-shot (QISS) magnetic resonance (MR) angiography, a nonenhanced two-dimensional electrocardiographically gated single-shot… Expand
A methodology to detect abnormal relative wall shear stress on the full surface of the thoracic aorta using four‐dimensional flow MRI
- P. Ooij, W. Potters, +6 authors Alex J. Barker
- Medicine, Chemistry
- Magnetic resonance in medicine
- 1 March 2015
To compute cohort‐averaged wall shear stress (WSS) maps in the thoracic aorta of patients with aortic dilatation or valvular stenosis and to detect abnormal regional WSS.
The clinical neurology of scrapie in Irish sheep.
- A. Healy, E. Weavers, +5 authors M. Doherty
- Journal of veterinary internal medicine
- 1 November 2003
One hundred twenty-nine sheep with scrapie were identified from 20 flocks in which scrapie previously had been confirmed. Physical and neurologic examinations were performed on all animals. Videotape… Expand
Accelerated dual‐venc 4D flow MRI for neurovascular applications
- S. Schnell, S. Ansari, +8 authors M. Markl
- Physics, Medicine
- Journal of magnetic resonance imaging : JMRI
- 1 July 2017
To improve velocity‐to‐noise ratio (VNR) and dynamic velocity range of 4D flow magnetic resonance imaging (MRI) by using dual‐velocity encoding (dual‐venc) with k‐t generalized autocalibrating… Expand
Viscous energy loss in the presence of abnormal aortic flow
To present a theoretical basis for noninvasively characterizing in vivo fluid‐mechanical energy losses and to apply it in a pilot study of patients known to express abnormal aortic flow patterns.
Aortic valve‐mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve‐associated aortopathy
- E. Bollache, David G. Guzzardi, +10 authors P. Fedak
- The Journal of thoracic and cardiovascular…
- 1 December 2018
Objectives: The objectives of this study were to investigate an association between the magnitude of flow‐mediated aortic wall shear stress (WSS) and medial wall histopathology in patients with… Expand
MR and CT Imaging for the Evaluation of Pulmonary Hypertension.
Imaging plays a central role in the diagnosis and management of all forms of pulmonary hypertension (PH). Although Doppler echocardiography is essential for the evaluation of PH, its ability to… Expand