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Cardioacceleratory responses to hypocretin-1 injections into rostral ventromedial medulla
The effects of microinjections of hcrt-1 into the rostral ventromedial medulla (RVMM) on mean arterial pressure, heart rate and the arterial baroreflex are investigated to suggest that hcrT-1 in the RVMM region activates neuronal circuits that both inhibit vagal activity and increase sympathetic activity to the heart, and that it alters the excitability of central circuits that reflexly control the circulation. Expand
Brainstem projections of aortic baroreceptor afferent fibers in the rat
  • J. Ciriello
  • Medicine, Biology
  • Neuroscience Letters
  • 28 March 1983
Brainstem projections of the aortic nerve in the rat were studied using the transganglionic transport of horseradish peroxidase to provide evidence of direct aorto-baroreceptor afferent projections to restricted regions of the solitary complex and indicate that these specific areas function in the integration of the baroreceptor reflex. Expand
Collateral axonal projections from hypothalamic hypocretin neurons to cardiovascular sites in nucleus ambiguus and nucleus tractus solitarius
Retrograde tract-tracing techniques combined with immunohistochemistry indicate that axons from hcrt-1 neurons bifurcate to innervate functionally similar cardiovascular-responsive sites in the NTS and Amb may represent the anatomical substrate by which the lateral hypothalamic hcrT-1 neuron simultaneously coordinate autonomic-cardiovascular responses to different behaviors. Expand
Effects of plasma angiotensin II and hypernatremia on subfornical organ neurons.
The data suggest that blood-borne ANG II and plasma hypernatremia can influence arterial pressure and the release of vasopressin from the neurohypophysis by altering the discharge rate of SFO neurons projecting to forebrain structures that contain magnocellular neurosecretory vasoppressin neurons and neurons that are components of sympathoexcitatory pathways. Expand
Innervation of the amygdaloid complex by catecholaminergic cell groups of the ventrolateral medulla
The projections to the amygdaloid complex (AMG) were studied in the rat by using either the retrograde tracer fluorogold (FG) or the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHA‐L) in combination with tyrosine hydroxylase (TH) and/or phenylethanolamine‐N‐methyltransferase (PNMT) immunohistochemistry. Expand
Effect of lesions of forebrain circumventricular organs on c-fos expression in the central nervous system to plasma hypernatremia
Investigation of the effect of selective ablation of the subfornical organ, and/or the anteroventral third ventricular region on the induction of Fos in central structures in response to plasma hypernatremia suggests changes in plasma osmolality and/ or concentration of sodium alter the activity of SON and brainstem neurons in the absence of afferent inputs. Expand
Fos induction in central structures after afferent renal nerve stimulation
Data indicate that ARN information originating in renal receptors is conveyed to a number of central areas known to be involved in the regulation of body fluid balance and arterial pressure, and suggest that this afferent information is an important component of central mechanisms regulating these homeostatic functions. Expand
Co-localization of estrogen and angiotensin receptors within subfornical organ neurons
The data suggest that E(2) may alter the physiological responses of SFO neurons to angiotensin II by down regulating the number of AT(1)R. Expand
Collateral axonal projections from ventrolateral medullary non-catecholaminergic neurons to central nucleus of the amygdala
Data demonstrate that axons originating from non-catecholaminergic neurons in VLM bifurcate to innervate ACe bilaterally, and may be the anatomical substrate by which VLM neurons relay simultaneously autonomic and/or visceral sensory information to influence the activity of ACe. Expand
Horseradish peroxidase study of brain stem projections of carotid sinus and aortic depressor nerves in the cat.
Data demonstrate that different regions of the solitary complex receive direct inputs from either one or both buffer nerves, suggesting a degree of separation of central pathways carrying CSN and ADN afferent information. Expand