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Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families.
BACKGROUND & AIMS Patients with severe bile salt export pump (BSEP) deficiency present as infants with progressive cholestatic liver disease. We characterized mutations of ABCB11 (encoding BSEP) inExpand
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Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency
Hepatocellular carcinoma (HCC) is rare in young children. We attempted to see if immunohistochemical and mutational‐analysis studies could demonstrate that deficiency of the canalicular bile acidExpand
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Histological healing after infliximab induction therapy in children with ulcerative colitis.
AIM To verify the impact of induction therapy with infliximab (IFX) on mucosal healing in children with ulcerative colitis (UC). METHODS The study included all UC pediatric patients treated withExpand
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Inter-observer variability in histopathological assessment of liver biopsies taken in a pediatric open label therapeutic program for chronic HBV infection treatment.
AIM To our knowledge, the inter-observer variability of the liver biopsy findings in HBV-infected children have not been studied as yet. Hence, we aimed to compare different pathologist's assessmentExpand
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The limited prognostic value of liver histology in children with biliary atresia.
UNLABELLED Background and rationale for the study. The aim of the study was to determine the prognostic value of histopathological findings with special care to the severity of liver fibrosis at theExpand
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Congenital hepatic fibrosis in a 9-year-old female patient – a case report
Congenital hepatic fibrosis (CHF) is a rare, autosomal recessive disorder, clinically characterized by hepatic fibrosis and portal hypertension. CHF results from ductal plate malformation (DPM) ofExpand
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Enhanced gastric IL-18 mRNA expression in Helicobacter pylori-infected children is associated with macrophage infiltration, IL-8, and IL-1&bgr; mRNA expression
Objective To investigate IL-18 mRNA expression in the gastric mucosa in Helicobacter pylori-infected children and its association with macrophage infiltration, IL-8, and IL-1&bgr; mRNA expression.Expand
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Recurrence of non‐alcoholic steatohepatitis after liver transplantation in a 13‐yr‐old boy
Abstract:  Nonalcoholic steatohepatitis (NASH) is the most severe form of non‐alcoholic fatty liver disease (NAFLD). The aim of our study was to highlight NASH as a rare but possible problem inExpand
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Hepatitis B virus genotypes in children with chronic hepatitis B in Poland
Objectives To analyse the distribution of HBV genotypes in Polish children with chronic hepatitis B, and to assess the relation between the viral genotype and the severity of liver damage. MethodsExpand
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Composition of inflammatory infiltrate and its correlation with HBV/HCV antigen expression.
AIM To study the composition of liver inflammatory infiltrate in biopsy material from patients chronically infected with hepatotropic viruses and to evaluate the correlation of inflammatoryExpand
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