• Publications
  • Influence
Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten
The flavonoids quercetin, (+)-dihydroquercetin, and quercetin 3-methyl ether were isolated from the ethyl acetate fractions of the fruits and stems of Opuntia ficus-indica var. saboten. In theExpand
  • 249
  • 6
Antioxidant and neuroprotective effects of hesperidin and its aglycone hesperetin
  • J. Cho
  • Chemistry, Medicine
  • Archives of pharmacal research
  • 1 August 2006
The present study evaluated antioxidant and neuroprotective activities of hesperidin, a flavanone mainly isolated from citrus fruits, and its aglycone hesperetin using cell-free bioassay system andExpand
  • 123
  • 5
Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus.
Previous reports have shown that the methanol extract and the essential oil from Acori graminei Rhizoma (AGR) inhibited excitotoxic neuronal cell death in primary cultured rat cortical cells. In theExpand
  • 98
  • 4
Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases
Chemokines are members of the chemoattractant cytokine family. They play key roles in the trafficking of leukocytes and in the induction of chemotaxis through the activation of G protein-coupledExpand
  • 105
  • 3
The ethyl acetate fraction from Physalis alkekengi inhibits LPS-induced pro-inflammatory mediators in BV2 cells and inflammatory pain in mice.
ETHNOPHARMACOLOGICAL RELEVANCE Physalis alkekengi is an edible herb whose fruit and calyx are traditionally used to treat a wide range of diseases including inflammation, toothache, and rheumatism.Expand
  • 21
  • 3
Memory enhancing and neuroprotective effects of selected ginsenosides
The effects of ginsenosides Rg3(R), Rg3(S) and Rg5/Rk1 (a mixture of Rg5 and Rk1, 1:1, w/w), which are components isolated from processedPanax ginseng C.A. Meyer (Araliaceae), on memory dysfunctionExpand
  • 86
  • 2
Antioxidant and memory enhancing effects of purple sweet potato anthocyanin and cordyceps mushroom extract
The effects of purple sweet potato anthocyanin (SPA) and Cordyceps mushroom extract (CME) on lipid peroxidation, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and cognitive deficits were examined.Expand
  • 109
  • 2
Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders
Protein misfolding, which is known to cause several serious diseases, is an emerging field that addresses multiple therapeutic areas. Misfolding of a disease-specific protein in the central nervousExpand
  • 26
  • 2
Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells.
  • J. Cho, H. Lee
  • Biology, Medicine
  • European journal of pharmacology
  • 6 February 2004
The present study evaluated effects of wogonin (5,7-dihydroxy-8-methoxyflavone) on excitotoxic and oxidative stress-induced neuronal damage in primary cultured rat cortical cells. Wogonin was shownExpand
  • 69
  • 1
Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion.
  • J. Cho, H. Lee
  • Medicine
  • Biological & pharmaceutical bulletin
  • 1 October 2004
The present study evaluated the effect of wogonin, a flavonoid originated from the root of Scutellaria baicalensis GEORGI, on focal ischemic brain injury in rats. Focal brain ischemia was induced byExpand
  • 54
  • 1
  • PDF