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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are key regulators of the apoptotic process. This family comprises proapoptotic and prosurvival proteins, and shifting the balance toward theExpand
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The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila.
In Drosophila, the secreted BMP-binding protein Short gastrulation (Sog) inhibits signaling by sequestering BMPs from receptors, but enhances signaling by transporting BMPs through tissues. We showExpand
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Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum
Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum
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A statistical analysis of a residential energy consumption survey study in Hangzhou, China
Abstract Households are major contributors to the emission of greenhouse gases and, consequently, to global warming. The past decades have seen significant improvements in building energy efficiencyExpand
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The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
IntroductionThe aim was to determine the effect of the Bruton tyrosine kinase (Btk)-selective inhibitor PCI-32765, currently in Phase I/II studies in lymphoma trials, in arthritis and immune-complexExpand
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Impact on the Endoplasmic Reticulum and Golgi Apparatus of Turnip Mosaic Virus Infection
ABSTRACT The impact of turnip mosaic virus (TuMV) infection on the endomembranes of the host early secretory pathway was investigated using an infectious clone that has been engineered for taggingExpand
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Oribatid mites of China: a review of progress, with a checklist*
The present paper gives a review of the taxonomic study on the suborder Oribatida (the cohort Astigmata excepted) in China including Hong Kong and Taiwan, with a checklist of 599 species andExpand
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Phylogenetic analysis of vertebrate CXC chemokines reveals novel lineage specific groups in teleost fish.
  • J. Chen, Q. Xu, +7 authors J. Zou
  • Biology, Medicine
  • Developmental and comparative immunology
  • 1 October 2013
In this study, we have identified 421 molecules across the vertebrate spectrum and propose a unified nomenclature for CXC chemokines in fish, amphibians and reptiles based on phylogenetic analysis.Expand
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Structure of the histone chaperone ASF1 bound to the histone H3 C-terminal helix and functional insights.
Asf1 is a histone chaperone that favors histone H3/H4 assembly and disassembly. We solved the structure of the conserved domain of human ASF1A in complex with the C-terminal helix of histone H3 usingExpand
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