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Evidence of an immune-mediated mechanism for an idiosyncratic nevirapine-induced reaction in the female Brown Norway rat.
- J. Shenton, M. Popović, J. Chen, M. Masson, J. Uetrecht
- Chemistry, Medicine
- Chemical research in toxicology
- 1 December 2005
Previously, we reported a new animal model of an idiosyncratic drug reaction in which nevirapine causes a skin rash in some rats that has characteristics similar to the reaction that occurs in… Expand
Lifestyle and health-related quality of life: A cross-sectional study among civil servants in China
BackgroundHealth-related quality of life (HRQoL) has been increasingly acknowledged as a valid and appropriate indicator of public health and chronic morbidity. However, limited research was… Expand
Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.
It is well documented that 5-10% hepatitis B adult vaccinees are non- and hypo-responders and probably are not adequately protected against hepatitis B virus (HBV) infection. The sequence variations… Expand
Resveratrol reverses multidrug resistance in human breast cancer doxorubicin-resistant cells
- F. Huang, Xiao-Nan Wu, J. Chen, Wenxiang Wang, Zufu Lu
- Experimental and therapeutic medicine
- 3 April 2014
Although its mechanisms remain unidentified, resveratrol (trans-3,4′,5-trihydroxystilbene; RES), which is an active, low molecular-weight compound, possesses a unique antitumor function and is… Expand
Sleep Deprivation Promotes Habitual Control over Goal-Directed Control: Behavioral and Neuroimaging Evidence
Sleep is one of the most fundamental processes of life, playing an important role in the regulation of brain function. The long-term lack of sleep can cause memory impairments, declines in learning… Expand
Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180
BackgroundDevelopmental iodine deficiency results in inadequate thyroid hormone (TH), which damages the hippocampus. Here, we explored the roles of hippocampal doublecortin and neural cell adhesion… Expand
High-mobility group protein B1 (HMGB1) is a novel biomarker for human ovarian cancer.
BACKGROUND High mobility group box l (HMGB1), a nuclear and extracellular protein, is implicated in some physiologic and pathologic conditions. In this study, we investigated the expression and… Expand
Neutralization of interleukin-17A delays progression of silica-induced lung inflammation and fibrosis in C57BL/6 mice.
Silica exposure can cause lung inflammation and fibrosis, known as silicosis. Interleukin-17A (IL-17A) and Th17 cells play a pivotal role in controlling inflammatory diseases. However, the roles of… Expand
Alexithymia and emotional regulation: A cluster analytical approach
BackgroundAlexithymia has been a familiar conception of psychosomatic phenomenon. The aim of this study was to investigate whether there were subtypes of alexithymia associating with different traits… Expand
Long noncoding RNA HOTAIR knockdown inhibits autophagy and epithelial-mesenchymal transition through the Wnt signaling pathway in radioresistant human cervical cancer HeLa cells.
- Xinggang Guo, Hongqi Xiao, +4 authors G. Lou
- Chemistry, Medicine
- Journal of cellular physiology
- 1 April 2019
Cervical cancer is one of the most common female malignancies around the world, and radiation resistance is a major obstacle to cancer therapy. Previously, overexpression of the long noncoding… Expand