Author pages are created from data sourced from our academic publisher partnerships and public sources.
α-Tocopherol Reduces Proteinuria, Oxidative Stress, and Expression of Transforming Growth Factor β1 in IgA Nephropathy in the Rat
Abstract Oxidative stress and the fibrogenic cytokine transforming growth factor β1 (TGFβ1) have been implicated in the pathogenesis and progression of IgA nephropathy. In the present study, we used… Expand
Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study
IgA nephropathy is the world's most common primary glomerulonephropathy. Recent evidence in a rat model implicated excessive production of oxygen-free radicals in the pathogenesis and suggested that… Expand
Evaluation of the hypertensive infant: a rational approach to diagnosis.
- Christopher G Roth, S. Spottswood, J. Chan, K. S. Roth
- Radiologic clinics of North America
- 1 September 2003
This article reviews the literature and describes a methodologic approach to the diagnosis of hypertension in the young infant. The numerous etiologies of hypertension have been discussed and… Expand
Understanding Bartter syndrome and Gitelman syndrome
BackgroundWe aim to review the clinical features of two renal tubular disorders characterized by sodium and potassium wasting: Bartter syndrome and Gitelman syndrome.Data sourcesSelected key… Expand
Obstructive Uropathy: An Important Cause of Chronic Renal Failure in Children
Care of individuals with renal failure continues to impose a tremendous burden on our national health care budget. Chronic renal failure is the final common denominator of a multiplicity of… Expand
Kidney failure in infants and children.
1. James C. M. Chan, MD*† 2. Debra M. Williams, MD* 3. Karl S. Roth, MD*† 1. *Department of Pediatrics, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 2.… Expand
Effects of I ,25-Dihydroxyvitamin-D3 on Renal Function, Mineral Balance, and Growth in Children with Severe Chronic Renal Failure
: To confirm and extend previous observations of enhanced linear growth in children with chronic renal disease being treated with 1,25-dihydroxyvitamin-D3 and to characterize further the calcium,… Expand
Hyperalimentation with amino acid and casein hydrolysate solutions. Mechanism of acidosis.
Four premature infants aged 1 to 2 weeks and one 10-year-old child who developed metabolic acidosis (base excess [BE], —9 to —17 mEq/liter) with continuous intravenous amino acid alimentation for… Expand
α-Tocopherol modulates lipoprotein cytotoxicity in obstructive nephropathy
- P. Saborío, R. J. Krieg Jr., N. Kuemmerle, E. Norkus, C. Schwartz, J. Chan
- Pediatric Nephrology
- 19 July 2000
Abstract Oxidative stress in unilateral ureteral obstruction (UUO) contributes to the development of glomerular and tubulointerstitial lesions. The present study investigated whether oxidized… Expand