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α-Tocopherol Reduces Proteinuria, Oxidative Stress, and Expression of Transforming Growth Factor β1 in IgA Nephropathy in the Rat
Abstract Oxidative stress and the fibrogenic cytokine transforming growth factor β1 (TGFβ1) have been implicated in the pathogenesis and progression of IgA nephropathy. In the present study, we usedExpand
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Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study
IgA nephropathy is the world's most common primary glomerulonephropathy. Recent evidence in a rat model implicated excessive production of oxygen-free radicals in the pathogenesis and suggested thatExpand
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Evaluation of the hypertensive infant: a rational approach to diagnosis.
This article reviews the literature and describes a methodologic approach to the diagnosis of hypertension in the young infant. The numerous etiologies of hypertension have been discussed andExpand
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Understanding Bartter syndrome and Gitelman syndrome
BackgroundWe aim to review the clinical features of two renal tubular disorders characterized by sodium and potassium wasting: Bartter syndrome and Gitelman syndrome.Data sourcesSelected keyExpand
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Obstructive Uropathy: An Important Cause of Chronic Renal Failure in Children
Care of individuals with renal failure continues to impose a tremendous burden on our national health care budget. Chronic renal failure is the final common denominator of a multiplicity ofExpand
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Kidney failure in infants and children.
1. James C. M. Chan, MD*† 2. Debra M. Williams, MD* 3. Karl S. Roth, MD*† 1. *Department of Pediatrics, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 2.Expand
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Effects of I ,25-Dihydroxyvitamin-D3 on Renal Function, Mineral Balance, and Growth in Children with Severe Chronic Renal Failure
: To confirm and extend previous observations of enhanced linear growth in children with chronic renal disease being treated with 1,25-dihydroxyvitamin-D3 and to characterize further the calcium,Expand
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Hyperalimentation with amino acid and casein hydrolysate solutions. Mechanism of acidosis.
Four premature infants aged 1 to 2 weeks and one 10-year-old child who developed metabolic acidosis (base excess [BE], —9 to —17 mEq/liter) with continuous intravenous amino acid alimentation forExpand
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α-Tocopherol modulates lipoprotein cytotoxicity in obstructive nephropathy
Abstract Oxidative stress in unilateral ureteral obstruction (UUO) contributes to the development of glomerular and tubulointerstitial lesions. The present study investigated whether oxidizedExpand
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Diagnosis and management of nasal fractures
The nasal bony–cartilaginous framework provides support to the nose and maintains airway patency. The cartilaginous and bony components are both susceptible to fracture. Nasal fractures are one ofExpand
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