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Assessing the Costs and Benefits of Brokers in the Mutual Fund Industry
Many investors purchase mutual funds through intermediated channels, paying brokers or financial advisors for fund selection and advice. This article attempts to quantify the benefits that investorsExpand
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Severe hypoglycemia and risks of vascular events and death.
BACKGROUND Severe hypoglycemia may increase the risk of a poor outcome in patients with type 2 diabetes assigned to an intensive glucose-lowering intervention. We analyzed data from a large study ofExpand
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Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.
BACKGROUND High blood pressure and stroke are associated with increased risks of dementia and cognitive impairment. This study aimed to determine whether blood pressure lowering would reduce theExpand
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Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes.
We investigated the effects of urinary albuminuria and reduced estimated GFR (eGFR on the risk for cardiovascular and renal events in 10,640 patients with available data. Expand
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Randomised trial of a perindopril-based blood pressure lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack
Background Blood pressure is a determinant of the risk of stroke among both hypertensive and non-hypertensive individuals with cerebrovascular disease. However, there is uncertainty about theExpand
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Default Risk Cannot Explain the Muni Puzzle: Evidence from Municipal Bonds that are Secured by U.S. Treasury Obligations
Fama (1977) and Miller (1977) predict that one minus the corporate tax rate will equate after-tax yields from comparable taxable and tax-exempt bonds. Empirical evidence shows that long-termExpand
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Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage.
BACKGROUND Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. METHODS We randomly assigned 2839 patients who had hadExpand
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Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial
Objective To explore the likely optimum blood pressure (BP) level for patients with a history of cerebrovascular disease. Methods The Perindopril Protection Against Recurrent Stroke Study (PROGRESS)Expand
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Effects of Perindopril-Based Lowering of Blood Pressure on Intracerebral Hemorrhage Related to Amyloid Angiopathy: The PROGRESS Trial
Background and Purpose— Patients with cerebral amyloid angiopathy (CAA) are at high risk for intracerebral hemorrhage (ICH), but no effective prevention strategies have been established. TheExpand
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