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Quantification of F-ring isoprostane-like compounds (F4-neuroprostanes) derived from docosahexaenoic acid in vivo in humans by a stable isotope dilution mass spectrometric assay.
Lipid peroxidation has been implicated in the pathophysiological sequelae of human neurodegenerative disorders. It is recognized that quantification of lipid peroxidation is best assessed in vivo byExpand
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An enantioselective synthesis of (−)-slaframine
Abstract An enantioselective synthesis of (−)-slaframine ( 1 ) has been accomplished by an intramolecular azide [2+3] dipolar cycloaddition starting from the readily available aldehyde 12 .
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Nucleophilic attack on 4,6-dimethoxy-2-pyrones; discovery of a remarkably facile rearrangement of the pyrones
Abstract During the course of mechanistic investigations of nucleophilic attach on 4,6-dimethoxy-2-pyrones, a rapid scrambling reaction has been found between 4,6-dimethoxy-3-methyl-2-pyrone and theExpand
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Synthetic Approaches to Ingenol
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Stereochemistry of palytoxin. 4. Complete structure
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