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Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration
Failure of the human embryo to implant into the uterine wall during the early stages of pregnancy is a major cause of infertility. Implantation involves embryo apposition and adhesion to theExpand
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Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity.
OBJECTIVE To evaluate the phenotype, proliferative, and differentiation capacities in vitro of stromal cells derived from peritoneal, ovarian, and deeply infiltrating endometriosis. DESIGNExpand
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Human Endometrial Stromal Cell Rho GTPases Have Opposing Roles in Regulating Focal Adhesion Turnover and Embryo Invasion In Vitro1
Implantation of the embryo into the uterine compartment is a multistep event involving attachment of the embryo to the endometrial epithelia, followed by invasion of the embryo through theExpand
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Endometrial cells from women with endometriosis have increased adhesion and proliferative capacity in response to extracellular matrix components: towards a mechanistic model for endometriosis
BACKGROUND Endometriosis, classified as the presence of endometrial cells in ectopic sites, is a debilitating disease causing pain and infertility in approximately 10% of women of reproductive age.Expand
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Effects of gonadotrophin releasing hormone analogues on human endometrial stromal cells and embryo invasion in vitro.
BACKGROUND Gonadotrophin releasing hormone (GnRH) analogues are widely used in IVF programmes as a method of suppressing the luteinizing hormone (LH) surge prior to ovarian stimulation, but theirExpand
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Halogenated biphenyl transport by blood components.
Halogenated biphenyl transport by components of rat blood was studied under both in vivo and in vitro conditions. Fractionation of plasma components by gel filtration, ultracentrifugation, andExpand
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Changes in cardiac glycoside receptor sites, 86rubidium uptake and intracellular sodium concentrations in the erythrocytes of patients receiving digoxin during the early phases of treatment of
1 Measurements of the binding of 12-alpha-[3H]-digoxin to the membranes of intact erythrocytes, erythrocytic 86rubidium uptake and intraerythrocytic sodium concentrations have been made in the redExpand
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Pharmacological evidence of calcium-activated and voltage-gated potassium channels in human platelets.
1. Previous electrophysiological studies have suggested the presence of KCa and Kv channels in human platelets. However, the pharmacology of these channels has not been defined. 2. We have studiedExpand
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Renin substrate in plasma of unanaesthetized pregnant ewes and their foetal lambs.
1. In unanaesthetized preparations 6-14 days after catheterization, the concentration of renin substrate (AI 212 +/- 20 ng/ml. S.E. of mean) in the plasma of foetal lambs during the last third ofExpand
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The effects of 5-HT and m-chlorophenylpiperazine (m-CPP) on the efflux of [3H]-5-HT from human perfused platelets.
1. m-Chlorophenylpiperazine (m-CPP), a 5-HT1c-receptor agonist, induces migraine-like headaches when taken orally by migraine sufferers. The present study was undertaken to see what effects m-CPP hadExpand
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