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SDF‐1 (CXCL12) Is Upregulated in the Ischemic Penumbra Following Stroke: Association with Bone Marrow Cell Homing to Injury
The chemokine stromal-derived factor-1 (SDF-1, also known as CXCL12) and its receptor CXCR4 have been implicated in homing of stem cells to the bone marrow and the homing of bone marrow-derived cellsExpand
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Exercise hyperventilation in patients with McArdle's disease.
This study was undertaken to determine if patients who lack muscle phosphorylase (i.e., McArdle's disease), and therefore the ability to produce lactic acid during exercise, demonstrate a normalExpand
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BrdU-positive cells in the neonatal mouse hippocampus following hypoxic-ischemic brain injury
BackgroundMechanisms that affect recovery from fetal and neonatal hypoxic-ischemic (H-I) brain injury have not been fully elucidated. The incidence of intrapartum asphyxia is approximately 2.5%, butExpand
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NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells.
Reperfusion injury is mediated, in part, by the upregulated expression of genes in microvascular endothelial cells that encode for inflammatory cytokines and adhesion molecules. The redox-regulatedExpand
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Facioscapulohumeral dystrophy associated with hearing loss and coats syndrome
Two unrelated cases of infantile facioscapulohumeral dystrophy (FSHD) with Coats syndrome of the retina and sensorineural hearing loss are described. Children with otherwise unexplained visual orExpand
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The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury
BackgroundStromal cell-derived factor 1 (SDF-1 or CXCL12) is chemotaxic for CXCR4 expressing bone marrow-derived cells. It functions in brain embryonic development and in response to ischemic injuryExpand
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Increased serum creatine kinase after exercise
The effect of 2 hours of exercise on the serum creatine kinase (CK) level was investigated in 11 men and 9 women. The mean increase of CK 24 hours after exercise was significantly greater in men. TheExpand
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NF-κB is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells
Reperfusion injury is mediated, in part, by the upregulated expression of genes in microvascular endothelial cells that encode for inflammatory cytokines and adhesion molecules. The redox-regulatedExpand
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Update on stem cell therapy for cerebral palsy
  • J. Carroll, R. Mays
  • Biology, Medicine
  • Expert opinion on biological therapy
  • 10 March 2011
Introduction: Due to the publicity about stem cell transplantation for the treatment of cerebral palsy, many families seek information on treatment, and many travel overseas for cell transplantation.Expand
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A single therapeutic dose of valproate affects liver carbohydrate, fat, adenylate, amino acid, coenzyme A, and carnitine metabolism in infant mice: possible clinical significance.
We have previously reported that chronic valproate administration reduced ketonemia in suckling mice and fasting epileptic children. The present study demonstrates that even a single dose ofExpand
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