• Publications
  • Influence
Hempseed as a nutritional resource: An overview
TLDR
Hempseed has been used to treat various disorders for thousands of years in traditional oriental medicine, and recent clinical trials have identified hempseed oil as a functional food, and animal feeding studies demonstrate the long-standing utility of hempseed as an important food resource. Expand
Human Psychopharmacology of Hoasca, A Plant Hallucinogen Used in Ritual Context in Brazil
TLDR
Assessment of 15 long-term members of a syncretic church that utilizes hoasca as a legal, psychoactive sacrament as well as 15 matched controls with no prior history of hoasca ingestion revealed high functional status. Expand
Pharmacokinetics of Hoasca alkaloids in healthy humans.
TLDR
N,N-Dimethyltryptamine, harmine, harmaline and tetrahydroharmine are the characteristic alkaloids found in Amazonian sacraments known as hoasca, ayahuasca, and yajè and little is known of their pharmacokinetics. Expand
Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers
TLDR
Ayahuasca can be described as inducing changes in the perceptual, affective, cognitive, and somatic spheres, with a combination of stimulatory and visual psychoactive effects of longer duration and milder intensity than those previously reported for intravenously administered DMT. Expand
Quantitation of N,N-dimethyltryptamine and harmala alkaloids in human plasma after oral dosing with ayahuasca.
TLDR
The one-step extraction method for DMT and the protein precipitation method for the three harmala alkaloid afford rapid, sensitive, and quantitative analyses of these alkaloids with minimal analyte loss. Expand
Phytochemical Analyses of Banisteriopsis Caapi and Psychotria Viridis
TLDR
A broad range in alkaloid distribution was observed in both sample sets, and all B. caapi samples had detectable amounts of harmine, harmaline and tetrahydroharmine, while some samples of P. viridis had little or no detectable levels of N,N-dimethyltryptamine (DMT). Expand
Various Alkaloid Profiles in Decoctions of Banisteriopsis Caapi
  • J. Callaway
  • Medicine
  • Journal of psychoactive drugs
  • 1 June 2005
TLDR
The alkaloid composition of one decoctions of Banisteriopsis caapi did not change significantly after standing at room temperature for 80 days, but the initial acidic pH was neutralized by natural fermentation after 50 days. Expand
Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: a whole-hemisphere autoradiography study.
TLDR
A lower serotonin transporter density among the alcoholic subjects was observed, specifically in the so-called "affect" region, suggesting an association between ethanol addiction and dysfunctional serotonergic neurotransmission in this area. Expand
Efficacy of dietary hempseed oil in patients with atopic dermatitis
TLDR
Dietary hempseed oil caused significant changes in plasma fatty acid profiles and improved clinical symptoms of atopic dermatitis, and it is suggested that these improvements resulted from the balanced and abundant supply of PUFAs in this Hempseed oil. Expand
Determination of endocannabinoids in nematodes and human brain tissue by liquid chromatography electrospray ionization tandem mass spectrometry.
TLDR
Good accuracy and precision were obtained for concentrations within the calibration range of 0.4-70 nM and 40-11,000 nM for monitored N-acylethanolamides (NAEs) and acyl glycerols, respectively. Expand
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