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Microbial conversion of steroid compounds: recent developments
Steroid compounds can be ranked among the most widely marketed products from the pharmaceutical industry. Highly specific reactions are required to produce functionalized compounds with therapeuticExpand
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Real-time bioprocess monitoring: Part I: In situ sensors
In the past decades, biotechnology has exploded to a cutting edge industry and its economical significance is exponentially growing. Bioprocess efficiency, productivity and optimization areExpand
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Whole-cell biocatalysis in organic media
Abstract The use of water-immiscible organic solvents in whole-cell biocatalysis has been exploited for biotransformations involving sparingly water-soluble or toxic compounds. These systems canExpand
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Stem cell cultivation in bioreactors.
This review describes recent developments in the cultivation of stem cells in bioreactors, particularly considerations regarding critical culture parameters, possible bioreactor configurations, and integration of novel technologies in the bioprocess development stage. Expand
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Mouse embryonic stem cell expansion in a microcarrier-based stirred culture system.
Embryonic stem (ES) cells have the ability to differentiate in vitro into a wide variety of cell types with potential applications for tissue regeneration. However, a large number of cells areExpand
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A comparative study of biocatalysis in non-conventional solvents: Ionic liquids, supercritical fluids and organic media
The catalytic activities of cutinase immobilized on zeolite NaY and Candida antarctica lipase B immobilized on an acrylic resin (Novozym 453) were measured in a model transesterification reaction inExpand
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Ethanol biosensors based on alcohol oxidase.
The detection and quantification of ethanol with high sensitivity, selectivity and accuracy is required in many different areas. A variety of methods and strategies have been reported for theExpand
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Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.
Antigen-independent tonic signaling by chimeric antigen receptors (CARs) can increase differentiation and exhaustion of T cells, limiting their potency. Incorporating 4-1BB costimulation in CARs mayExpand
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Expansion of mouse embryonic stem cells on microcarriers
Embryonic stem (ES) cells have been shown to differentiate in vitro into a wide variety of cell types having significant potential for tissue regeneration. Therefore, the operational conditions forExpand
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Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System
Summary Oligodendrocyte precursor cells (OPCs) offer considerable potential for the treatment of demyelinating diseases and injuries of the CNS. However, generating large quantities of high-qualityExpand
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