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Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos
Pseudomonas aeruginosa is an opportunistic human pathogen that can cause serious infection in those with deficient or impaired phagocytes. We have developed the optically transparent and geneticallyExpand
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  • Open Access
Colorectal cancer incidence in Asian migrants to the United States and their descendants
AbstractObjectives: To examine the incidence of colorectal cancer among Asian residents of the United States according to country of birth. Methods: We determined the incidence of colorectal cancerExpand
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Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis.
Three structural features of lipid A (addition of palmitate [C16 fatty acid], addition of aminoarabinose [positively charged amino sugar residue], and retention of 3-hydroxydecanoate [3-OH C10 fattyExpand
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Staphylococcus aureus small-colony variants are independently associated with worse lung disease in children with cystic fibrosis.
BACKGROUND Cystic fibrosis (CF) lung disease is associated with diverse bacteria chronically infecting the airways. Slow-growing, antibiotic-resistant mutants of Staphylococcus aureus known asExpand
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Fifteen years of experience with bacterial meningitis.
BACKGROUND Introduction of Haemophilus influenzae type b (Hib) vaccines has dramatically altered the epidemiology of bacterial meningitis in children. The goal of this study was to describe theseExpand
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Lactate dehydrogenase isoenzyme-1: changes during the first day after acute myocardial infarction.
We studied the time course of change of lactate dehydrogenase isoenzyme-1 (LD-1) in serum of patients suspected of having had an acute myocardial infarction. LD-1 was measured at intervals of 4-8 hExpand
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  • Open Access
Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection
In cystic fibrosis (CF), conventional antibiotic susceptibility results correlate poorly with clinical outcomes. We hypothesized that biofilm testing would more accurately reflect theExpand
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Gastric intestinal metaplasia in ethnic groups in the southwestern United States.
The incidence of gastric cancer has declined dramatically in the United States during this century. However, the incidence of gastric cancer among Hispanics, Blacks, and Native Americans remainsExpand
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  • Open Access
Use of Pseudomonas biofilm susceptibilities to assign simulated antibiotic regimens for cystic fibrosis airway infection.
OBJECTIVES Increasing evidence indicates that Pseudomonas aeruginosa grows as a biofilm in the lungs of cystic fibrosis (CF) patients. In contrast, the bacterial inoculum used in conventionalExpand
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Childhood brain tumor risk in relation to birth characteristics.
A population-based case-control study was conducted utilizing linked cancer registry and birth certificate data to examine potential associations between selected birth characteristics and theExpand
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