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Tetrameric immune macroglobulins in three orders of bony fishes.
The immune IgM-like macroglobulins were isolated from three species of bony fishes (Ictalurus punctatus, Lepisosteus osseus, and Polyodon spathula) representing the three orders of the subclassExpand
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The molecular basis of antibody formation: a paradox.
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Physical and chemical characterization of an oyster hemagglutinin.
Abstract The natural hemagglutinin of the oyster Crassostrea virginica was examined for possible structural relationship with vertebrate immunoglobulins. The hemagglutinin activity was associatedExpand
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Primary structure of human J chain: alignment of peptides from chemical and enzymatic hydrolyses.
The primary structure of the J chain from a human Waldenströms IgM protein has been determined using a combination of automated and conventional Edman degradative procedures. Eighty-five percent ofExpand
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C1 fixation and classical complement pathway activation by a fragment of the Cmu4 domain of IgM
A 56 residue fragment derived from a Waldenstrome IgM protein and consisting of 24 residues of the amino-terminal portion of the Cmu4 domain disulfide bonded to 32 residues of the carboxy-terminalExpand
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Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily.
We have isolated and sequenced a 598-bp full length cDNA clone for the human Charcot-Leyden crystal (CLC) protein (eosinophil lysophospholipase), the unique and prominent constituent of humanExpand
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Secondary structure of the immunoglobulin J chain.
J chain is a 137-residue polypeptide that is covalently linked to polymeric immunoglobulins and participates in their synthesis and transport to external secretions. To clarify these roles, theExpand
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Isolation and characterization of the immune macroglobulin from the paddlefish, Polyodon spathula.
Abstract The immune macroglobulin from the paddlefish, Polyodon spathula, was purified and characterized physicochemically. The macroglobulin had a sedimentation coefficient of 14.2 S and a molecularExpand
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Studies of the component chains of human IgM by citraconylation.
Abstract Partial reduction and alkylation of a Waldenstrom IgM followed by reaction with citraconic anhydride resulted in modification of 92–95% of the free amino groups. The citraconylated μ and κExpand
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Purification and characterization of the gag gene products of avian-type C retroviruses by high-pressure liquid chromatography.
Abstract A rapid and efficient method for separating the translational products of the gag gene of avian-type C retroviruses by employing a high-resolution gel permeation column, high-pressure liquidExpand
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