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Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma.
- T. Kreisl, L. Kim, +10 authors H. Fine
- Journal of clinical oncology : official journal…
- 10 February 2009
PURPOSE To evaluate single-agent activity of bevacizumab in patients with recurrent glioblastoma. PATIENTS AND METHODS Patients with recurrent glioblastoma were treated with bevacizumab 10 mg/kg… Expand
SLC26A4/PDS genotype-phenotype correlation in hearing loss with enlargement of the vestibular aqueduct (EVA): evidence that Pendred syndrome and non-syndromic EVA are distinct clinical and genetic…
- S. Pryor, A. Madeo, +8 authors A. Griffith
- Biology, Medicine
- Journal of Medical Genetics
- 1 February 2005
Enlargement of the vestibular aqueduct (EVA) and its contents, the endolymphatic sac and duct, is the most common radiologic malformation of the inner ear associated with sensorineural hearing loss.1… Expand
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition.
- R. Goldbach-Mansky, Natalie J M Dailey, +37 authors D. Kastner
- The New England journal of medicine
- 10 August 2006
BACKGROUND Neonatal-onset multisystem inflammatory disease is characterized by fever, urticarial rash, aseptic meningitis, deforming arthropathy, hearing loss, and mental retardation. Many patients… Expand
Long-term natural history of hemangioblastomas in patients with von Hippel-Lindau disease: implications for treatment.
- J. Ammerman, R. Lonser, J. Dambrosia, J. Butman, E. Oldfield
- Journal of neurosurgery
- 1 August 2006
OBJECT In the course of their lives most patients with von Hippel-Lindau (VHL) disease require treatment for several symptom-producing hemangioblastomas of the cerebellum, brainstem, or spinal cord.… Expand
Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance imaging (MRI) studies have… Expand
Trading up : why consumers want new luxury goods--and how companies create them
Prospective natural history study of central nervous system hemangioblastomas in von Hippel-Lindau disease.
OBJECT The tumors most frequently associated with von Hippel-Lindau (VHL) disease are hemangioblastomas. While they are associated with significant neurological impairment and mortality, their… Expand
Cerebrovascular disease in HIV-infected pediatric patients: neuroimaging findings.
- A. D. Patsalides, L. Wood, G. Atac, E. Sandifer, J. Butman, N. Patronas
- AJR. American journal of roentgenology
- 1 October 2002
OBJECTIVE The goal of our study was to report on the prevalence and the neuroradiologic manifestations of cerebrovascular complications in children infected with HIV. We also elucidate the types of… Expand
Normal vision despite narrowing of the optic canal in fibrous dysplasia.
- J. Lee, E. Fitzgibbon, +5 authors M. Collins
- The New England journal of medicine
- 21 November 2002
BACKGROUND Fibrous dysplasia of bone frequently involves the anterior base of the cranium and results in encasement of the optic-nerve canals. It has been assumed that such encasement leads to… Expand
Single-trial fMRI Shows Contralesional Activity Linked to Overt Naming Errors in Chronic Aphasic Patients
- W. A. Postman-Caucheteux, R. Birn, +5 authors A. Braun
- Psychology, Medicine
- Journal of Cognitive Neuroscience
- 1 June 2010
We used fMRI to investigate the roles played by perilesional and contralesional cortical regions during language production in stroke patients with chronic aphasia. Expand