J. Butenhoff

Publications101
h-index50
Citations10,860
Highly Influential Citations958
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Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers
Background The presence of perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS), and perfluorooctanoate (PFOA) has been reported in humans and wildlife. Pharmacokinetic differences have… Expand
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Subchronic toxicity studies on perfluorooctanesulfonate potassium salt in cynomolgus monkeys.
This study was conducted to determine the earliest measurable response of primates to low-level perfluorooctanesulfonate (PFOS) exposure and to provide information to reduce uncertainty in human… Expand
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Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: postnatal evaluation.
The postnatal effects of in utero exposure to perfluorooctane sulfonate (PFOS, C8F17SO3-) were evaluated in the rat and mouse. Pregnant Sprague-Dawley rats were given 1, 2, 3, 5, or 10 mg/kg PFOS… Expand
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Quantitative characterization of trace levels of PFOS and PFOA in the Tennessee River.
Although there is evidence of widespread distribution of organic fluorochemicals such as perfluorooctane sulfonate and perfluorooctanoate, in the environment, the versatility of these compounds in… Expand
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Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations.
The maternal and developmental toxicities of perfluorooctane sulfonate (PFOS, C8F17SO3-) were evaluated in the rat and mouse. PFOS is an environmentally persistent compound used as a surfactant and… Expand
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The Toxicology of Perfluorooctanoate
ABSTRACT PFOA is a peroxisome proliferator (PPAR agonist) and exerts morphological and biochemical effects characteristic of PPAR agonists. These effects include increased β-oxidation of fatty acids,… Expand
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Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats.
Perfluorooctanesulfonate (PFOS) is a persistent acid found widely distributed in wildlife and humans. To understand the potential reproductive and developmental effects of PFOS, a two-generation… Expand
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Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats.
Perfluorooctanesulfonate (PFOS) is a widely disseminated persistent compound found at low (part-per-billion) concentrations in serum and liver samples from humans and fish-eating wildlife. This study… Expand
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The developmental toxicity of perfluoroalkyl acids and their derivatives.
Perfluoroalkyl acids such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have applications in numerous industrial and consumer products. Although the toxicology of some of… Expand
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Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague-Dawley rats: dose-response, and biochemical and pharamacokinetic parameters.
Perfluorooctanesulfonate (PFOS) is a widely distributed, environmentally persistent acid found at low levels in human, wildlife, and environmental media samples. Neonatal mortality has been observed… Expand
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