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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.
The addition of the measurement of C-reactive protein to screening based on lipid levels may provide an improved method of identifying persons at risk for cardiovascular events.
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus.
Elevated levels of CRP and IL-6 predict the development of type 2 DM, and data support a possible role for inflammation in diabetogenesis.
C-Reactive Protein, the Metabolic Syndrome, and Risk of Incident Cardiovascular Events: An 8-Year Follow-Up of 14 719 Initially Healthy American Women
These prospective data suggest that measurement of CRP adds clinically important prognostic information to the metabolic syndrome and is associated with increased levels of C-reactive protein (CRP).
Epidemiology in Medicine
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women.
In this cohort of initially healthy women, nonfasting triglyceride levels were associated with incident cardiovascular events, independent of traditional cardiac risk factors, levels of other lipids, and markers of insulin resistance; by contrast, fasting triglycerides showed little independent relationship.
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease.
In this trial among healthy men, 12 years of supplementation with beta carotene produced neither benefit nor harm in terms of the incidence of malignant neoplasms, cardiovascular disease, or death from all causes.
A Randomized Trial of Low-Dose Aspirin in the Primary Prevention of Cardiovascular Disease in Women
Subgroup analyses showed that aspirin significantly reduced the risk of major cardiovascular events, ischemic stroke, and myocardial infarction among women 65 years of age or older, leading to a nonsignificant finding with respect to the primary end point.
Low-density lipoprotein subclass patterns and risk of myocardial infarction.
The association of low-density lipoprotein (LDL) subclass patterns with coronary heart disease was investigated in a case-control study of nonfatal myocardial infarction and multivariate logistic regression analyses showed that both high-density cholesterol and triglyceride levels contributed to the risk associated with the small, dense LDL subclass pattern.
Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women.
CRP is a strong independent risk factor for cardiovascular disease that adds to the predictive value of risk models based on usual factors alone and was a predictor among subgroups of women with low as well as high risk as defined by other cardiovascular risk factors.