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Vascular Surgery I
Although general endotracheal anesthesia is still the most common type of anesthesia used in vascular patients, increasing evidence suggests that spinal or epidural anesthesia may be more appropriate, and the goals of the American Heart Association/American College of Cardiology should be targeted. Expand
Attachment of indium‐111 labelled endothelial cells to pretreated polytetrafluoroethylene vascular grafts
By pretreating with a substance such as fibronectin, the number of endothelial cells attaching to PTFE vascular grafts can be greatly increased, thereby enhancing the cell seeding process. Expand
The effect of varying fibronectin concentration on the attachment of endothelial cells to polytetrafluoroethylene vascular grafts.
Overall, fibronectin at a concentration of 20 micrograms/ml was found to be the most efficient in terms of cell attachment and cost since any further increase in concentration was not accompanied by increased cell attachment. Expand
Infrainguinal bypass surgery: Factors determining late graft patency
- J. Budd, J. Brennan, J. Beard, H. Warren, P. Burton, P. Bell
- The British journal of surgery
- 1 December 1990
The results suggest that prosthetic grafts are a suitable alternative to autogenous vein when the distal anastomosis is above the knee, but vein should always be used, if available, below the knee joint. Expand
The effect of preformed confluent endothelial cell monolayers on the patency and thrombogenicity of small calibre vascular grafts.
The use of preformed, confluent endothelial cell monolayers for seeding prosthetic grafts significantly reduces the early graft thrombogenicity and improves graft patency; it does not, however, completely halt the increase in throm bogenicity which occurs during the early post-implantation period. Expand
Platelet deposition after angioplasty is abolished by restoration of the endothelial cell monolayer.
The results illustrate that rapid reendothelialization of angioplasty sites decreases subsequent platelet deposition and may reduce the rate of acute arterial reocclusion complicating endovascular techniques. Expand
The effect of transluminal endothelial seeding on myointimal hyperplasia following angioplasty.
- M. Thompson, J. Budd, S. Eady, M. Underwood, R. James, P. Bell
- European journal of vascular surgery
- 1 June 1994
The results suggest that transluminal endothelial seeding may be a therapeutically applicable technique as it decreases myointimal hyperplasia, and increases patency following angioplasty, and indicates that intensive efforts should be made to preserve the endothelium during vascular reconstruction. Expand
Selection of patients with critical limb ischaemia for femorodistal vein bypass.
The results show that excellent limb salvage can be successfully achieved in severely ischaemic patients by adopting an aggressive approach to Femorodistal bypass, and that age, gender and poor medical condition are not contraindications to femorodistsal bypass. Expand
Effect of seeding time and density on endothelial cell attachment to damaged vascular surfaces
An in vitro model to facilitate the study of endothelial cell seeding of damaged vascular surfaces has been developed and, to achieve confluent cell attachment, a seeding density >5 × 105 cells/cm2 should be used. Expand
A method to transluminally seed angioplasty sites with endothelial cells using a double balloon catheter.
- M. Thompson, J. Budd, S. Eady, R. James, P. Bell
- European journal of vascular surgery
- 1 March 1993
Investigation of a method to transluminally deliver endothelial cells to angioplasty sites using a double balloon catheter with a central instillation port suggests that endothelium cells may be successfully delivered and retained on damaged vascular surfaces. Expand