J. Brust

Publications233
h-index39
Citations7,426
Highly Influential Citations181
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Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.
TLDR
It is concluded that neuropsychiatric disorders due to cobalamin deficiency occur commonly in the absence of anemia or an elevated mean cell volume and that measurements of serum methylmalonic acid and total homocysteine both before and after treatment are useful in the diagnosis of these patients.
Neurologic Aspects of Cobalamin Deficiency
TLDR
A wide variety of neurologic symptoms and signs were encountered, however, including ataxia, loss of cutaneous sensation, muscle weakness, diminished or hyperactive reflexes, spasticity, urinary or fecal incontinence, orthostatic hypotension, Loss of vision, dementia, psychoses, and disturbances of mood.
Musicophilia. Tales of Music and the Brain.
Systematic review: Efficacy and safety of medical marijuana in selected neurologic disorders
TLDR
A systematic review of medical marijuana to address treatment of symptoms of multiple sclerosis, epilepsy, and movement disorders found oral cannabinoids are of unknown efficacy in non–chorea-related symptoms of Huntington disease, Tourette syndrome, cervical dystonia, and epilepsy.
Leukoencephalopathy and raised brain lactate from heroin vapor inhalation (“chasing the dragon”)
TLDR
Elevated lactate in white matter and the possible response to antioxidants suggests mitochondrial dysfunction in progressive spongiform leukoencephalopathy following inhalation of heated heroin vapor.
The Man Who Mistook His Wife for a Hat and Other Clinical Tales
  • J. Brust
  • History
    Neurology
  • 1 December 1986
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Cerebrovascular complications of the use of the "crack" form of alkaloidal cocaine.
TLDR
There is a strong temporal association of the use of alkaloidal cocaine with both ischemic and hemorrhagic cerebrovascular events that should be part of the evaluation of any young patient with a stroke.
Ethanol and Cognition: Indirect Effects, Neurotoxicity and Neuroprotection: A Review
  • J. Brust
  • Medicine
    International journal of environmental research…
  • 1 April 2010
TLDR
Ethanol affects cognition in a number of ways and in sufficient dosage can cause lasting dementia, but in low-to-moderate dosage reduces the risk of dementia, including Alzheimer type.
Music and language: musical alexia and agraphia.
  • J. Brust
  • Psychology
    Brain : a journal of neurology
  • 1 June 1980
TLDR
Two aphasic right-handed professional musicians with left hemispheric lesions had disturbed musical function, especially musical alexia and agraphia, and in neither patient were those aspects of musical notation either closest to verbal language or most dependent upon temporal (sequential) processing maximally impaired.
Aphasia in Acute Stroke
TLDR
In both fluent and nonfluent groups, hemiparesis and/or visual field cut were associated with poor prognosis; among survivors, aphasia improved in 52%, and in only 13% did it clear completely.
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