Synthesis and transdermal penetration of NSAID glycoside esters.
Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.
Percutaneous delivery of carbamazepine and selected N-alkyl and N-hydroxyalkyl analogues.
Structure and synthesis of isoflavonoid analogues from Neorautanenia amboensis Schinz
The isolation and structural elucidation of six pterocarpans : neorautenane, neorautanol, edulenane, edulenanol ambonane, and neorautenanol, as well as two new isoflavanones : ambonone and…
Artemisinin-quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity.
Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids.
Synthesis, antimalarial activity and cytotoxicity of 10-aminoethylether derivatives of artemisinin.
Transdermal penetration of zalcitabine, lamivudine and synthesised N-acyl lamivudine esters.
Degradation of trimethoprim.
The structures of these compounds were determined by physical methods and it was found that the resonance of C-5 in the 13C NMR spectrum is indicative of the substitution pattern of the resultant amino hydroxy pyrimidines.
Synthesis of methoxypoly(ethylene glycol) carbonate prodrugs of zidovudine and penetration through human skin in vitro
A series of novel methoxypoly (ethylene glycol) carbonate prodrugs of the antiretroviral drug zidovudine (azidothymidine, AZT) are synthesised in an attempt to enhance the physicochemical properties for transdermal delivery, which may reduce the severe side‐effects and toxicity associated with high oral doses of AZT.