Synthesis and transdermal penetration of NSAID glycoside esters.
- H. Swart, J. Breytenbach, J. Hadgraft, J. du Plessis
- Chemistry, MedicineInternational journal of pharmaceutics
- 14 September 2005
Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.
- M. C. Lombard, D. N'Da, L. Wiesner
- Chemistry, BiologyEuropean Journal of Pharmaceutical Sciences
- 18 December 2012
Percutaneous delivery of carbamazepine and selected N-alkyl and N-hydroxyalkyl analogues.
- L. Fourie, J. Breytenbach, J. du Plessis, C. Goosen, H. Swart, J. Hadgraft
- ChemistryInternational journal of pharmaceutics
- 26 July 2004
Structure and synthesis of isoflavonoid analogues from Neorautanenia amboensis Schinz
- J. Breytenbach, G. Rall
- Chemistry
- 1980
The isolation and structural elucidation of six pterocarpans : neorautenane, neorautanol, edulenane, edulenanol ambonane, and neorautenanol, as well as two new isoflavanones : ambonone and…
Artemisinin-quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity.
- M. C. Lombard, D. N'Da, J. Breytenbach, Peter J. Smith, C. Lategan
- ChemistryBioorganic & Medicinal Chemistry Letters
- 1 December 2010
Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids.
- M. C. Lombard, D. N'Da, J. Breytenbach, Peter J. Smith, C. Lategan
- Chemistry, BiologyBioorganic & Medicinal Chemistry Letters
- 15 March 2011
Synthesis, antimalarial activity and cytotoxicity of 10-aminoethylether derivatives of artemisinin.
- Theunis T. Cloete, J. Wilma Breytenbach, C. D. Kock, Peter J. Smith, J. Breytenbach, D. N'Da
- ChemistryBioorganic & Medicinal Chemistry
- 1 August 2012
Transdermal penetration of zalcitabine, lamivudine and synthesised N-acyl lamivudine esters.
- M. Gerber, J. Breytenbach, J. du Plessis
- Biology, ChemistryInternational journal of pharmaceutics
- 3 March 2008
Degradation of trimethoprim.
- J. Bergh, J. Breytenbach, P. Wessels
- ChemistryJournal of Pharmacy and Science
- 1 April 1989
The structures of these compounds were determined by physical methods and it was found that the resonance of C-5 in the 13C NMR spectrum is indicative of the substitution pattern of the resultant amino hydroxy pyrimidines.
Synthesis of methoxypoly(ethylene glycol) carbonate prodrugs of zidovudine and penetration through human skin in vitro
- D. N'Da, J. Breytenbach
- Biology, MedicineThe Journal of pharmacy and pharmacology
- 1 June 2009
A series of novel methoxypoly (ethylene glycol) carbonate prodrugs of the antiretroviral drug zidovudine (azidothymidine, AZT) are synthesised in an attempt to enhance the physicochemical properties for transdermal delivery, which may reduce the severe side‐effects and toxicity associated with high oral doses of AZT.
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