The book of GENESIS - exploring realistic neural models with the GEneral NEural SImulation System (2. ed.)
This publication explains how to use the GENESIS simulation/modeling software system available through the Internet file-server at the California Institute of Technology, Pasadena, California, USA.…
Simulation of networks of spiking neurons: A review of tools and strategies
- R. Brette, M. Rudolph-Lilith, A. Destexhe
- Computer ScienceJournal of Computational Neuroscience
- 28 November 2006
This work provides a series of benchmark simulations of different types of networks of spiking neurons, including Hodgkin–Huxley type, integrate-and-fire models, interacting with current-based or conductance-based synapses, using clock-driven or event-driven integration strategies.
The Book of GENESIS
The interpretation of the creation of the earth has been a theological debate for thousands of years by almost as many notable biblical scholars. “Old Earth” and “Young Earth” theorists alike, each…
An active membrane model of the cerebellar Purkinje cell. I. Simulation of current clamps in slice.
A detailed compartmental model of a cerebellar Purkinje cell with active dendritic membrane was constructed and generated two types of spiking behavior, which were robust to changes in the densities of all of the ionic channels.
Cerebellum Implicated in Sensory Acquisition and Discrimination Rather Than Motor Control
- Jianfeng Gao, L. Parsons, J. Bower, J. Xiong, Jinqi Li, P. Fox
- Psychology, BiologyScience
- 26 April 1996
These findings suggest that the lateral cerebellum may be active during motor, perceptual, and cognitive performances specifically because of the requirement to process sensory data.
A Comparative Survey of Automated Parameter-Search Methods for Compartmental Neural Models
Comparing the performance of four different parameter-search methods on several single-neuron models demonstrates that genetic algorithms and simulated annealing are generally the most effective methods.
Congruence of spatial organization of tactile projections to granule cell and Purkinje cell layers of cerebellar hemispheres of the albino rat: vertical organization of cerebellar cortex.
The view that short-latency afferent tactile projections to both the GC and PC layers of cerebellar cortex are highly organized spatially is supported, indicating that there is a vertical organization in GC-PC excitatory relations, while GC-induced PC inhibition is slightly more widely distributed.
An active membrane model of the cerebellar Purkinje cell II. Simulation of synaptic responses.
Both excitatory and inhibitory postsynaptic channels were added to a previously described complex compartmental model of a cerebellar Purkinje cell to examine model responses to synaptic inputs and showed that activation of P-type Ca2+ channels in both the smooth and spiny dendrites augmented the depolarization during the complex spike and that Ca(2+)-activated K-activated channels in the same dendritic regions determined the duration of the spike.
Oscillatory activity in the cerebellar hemispheres of unrestrained rats.
It is suggested that the oscillations recorded in the granule cell layer of cerebellar folium Crus IIa in unrestrained rats are an underlying dynamic property of the entire somatosensory network.
Cholinergic suppression specific to intrinsic not afferent fiber synapses in rat piriform (olfactory) cortex.
Differences in the cholinergic suppression of afferent and intrinsic fiber synaptic transmission were studied in the rat piriform cortex and the increase in the level of facilitation accompanying suppression suggests a presynaptic mechanism.