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Release of cytokines by blood monocytes during strenuous exercise.
During strenuous exercise in endurance athletes, monocytes are activated and there is an acute inflammation and hypoxemia possibly due to lesional pulmonary edema. IL-6 and TNF-alpha released byExpand
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Interleukins 1-beta, -8, and histamine increases in highly trained, exercising athletes.
PURPOSE Exercise-induced hypoxemia (EIH) in highly trained athletes is associated with an increase in histamine release (%H) during exercise. Certain cytokines, known as histamine-releasing factors,Expand
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An efficient proteomics-based approach for the screening of autoantibodies.
This study presents an improved method for the complete transfer of proteins separated by two-dimensional gel electrophoresis to a membrane, specifically designed for the screening and identificationExpand
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Cerebral metabolism in fetal lamb after maternal infusion of ethanol.
Cerebral uptake of glucose and O2 (VCO2) was measured in 10 chronically catheterized fetal lambs during a control period, after a 1-h maternal infusion of ethanol (1.0 g X kg-1 X h-1) and 1-hExpand
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Effects of maternal ethanol infusion on fetal cardiovascular and brain activity in lambs.
Ethanol (1 gm/kg of maternal body weight administered over 1 hour) was infused intravenously into 11 chronically prepared pregnant ewes between 128 to 137 days' gestation. Fetal breathing movementsExpand
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Increased expression of tissue inhibitor of metalloproteinase-1 and loss of correlation with matrix metalloproteinase-9 by macrophages in asthma.
Alveolar macrophages (AMs) can mediate tissue destruction and repair by synthesizing matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) as well as inflammatory cytokines, which regulateExpand
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Adenovirus-mediated in vivo gene transfer in guinea pig middle ear mucosa.
This article describes a study designed to assess the feasibility of using recombinant adenovirus for delivering therapeutic peptides in vivo in the guinea pig middle ear cleft. A recombinantExpand
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Basophils and exercise-induced hypoxemia in extreme athletes.
This study examined whether the increase in histamine release (%H, i.e., plasma histamine expressed as a percentage of whole blood histamine) associated with exercise-induced hypoxemia (EIH) isExpand
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Phenotypic heterogeneity studied by immunohistochemistry and aneuploidy in non-small cell lung cancers.
Non-small cell lung cancers (non-SCLC) differ from small cell lung cancers (SCLC) by many clinical features and prognosis. However, recent studies suggest that lung cancer heterogeneity frequentlyExpand
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Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4.
The involvement of cyclic nucleotides and of phosphodiesterase activities in IL-4-induced IgE production and release of the soluble form of the low affinity receptor for IgE (sCD23) by normal humanExpand
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