1H-NMR comparative studies of dinucleoside monophosphates. Influence of different factors on the conformational equilibria of nucleoside and dinucleoside monophosphates in aqueous solution
PMR-relaxation and steric computations give unequivocal nucleoside conformations.
Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thiethanes with Hypervalent Iodine Reagents.
The oxyalkynylation of thiiranes and thietanes is reported using ethynylbenziodoxolone reagents (EBXs) to readily access functionalized building blocks bearing an alkynyl, a benzoate, and an iodide group with high atom efficiency.
Copper-Catalyzed Alkynylation of Hydrazides: An Easy Access to Functionalized Azadipeptides.
A copper-catalyzed alkynylation of azadipeptides using ethynylbenziodoxolone (EBX) reagents is reported, compatible with most functional groups naturally occurring on amino acid side chains and allows the transfer of silyl-, alkyl-, and aryl-substituted alkynes.
Tosyloxybenziodoxolone: A Platform for Performing the Umpolung of Alkynes in One-Pot Transformations.
A one-pot, two-step process for EBX generation and their direct application in substrate functionalization is reported, enabling the originally mandatory isolation and purification of the reagents to be bypassed, resulting in a more efficient synthesis.