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Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells.
Cell cycle progression is regulated by a wide variety of external factors, amongst them are growth factors and extracellular matrix factors. During the last decades evidence has been obtained thatExpand
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A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrix.
Several enzymes involved in the phosphoinositide metabolism have been shown to be present in nuclei of rat liver and Friend cells. In this paper we demonstrate that nuclear matrices of mouse NIHExpand
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Identification of connexin43 as a functional target for Wnt signalling.
Wnt mediated signal transduction is considered to regulate activity of target genes. In Xenopus embryos, ectopic Wnt1 and Wnt8 expression induces gap-junctional communication. During murine brainExpand
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Cell fate determination during G1 phase progression
Abstract.During the cell cycle, a cell may encounter one of five different fates: it can proliferate, differentiate, become quiescent or senescent, or go into apoptosis. The initiation of such fatesExpand
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Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors
Many cell types display two classes of epidermal growth factor receptor (EGFR) as judged from EGF binding studies; i.e., a major class of low affinity EGFR and a minor class of high affinity EGFR. WeExpand
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Three classes of epidermal growth factor receptors on HeLa cells.
The kinetics of 125I-labeled epidermal growth factor (EGF) binding to receptors on HeLa cells were investigated. Scatchard analysis revealed the presence of 22,000 high affinity receptors (Kd = 0.12Expand
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The epidermal growth factor.
Epidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to theExpand
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Glucose Repression in Saccharomyces cerevisiae Is Related to the Glucose Concentration Rather Than the Glucose Flux*
Glucose plays an important regulatory role in the yeast Saccharomyces cerevisiae, which is mostly reflected at the transcriptional level by glucose repression. The signal that initiates glucoseExpand
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HXT5 expression is determined by growth rates in Saccharomyces cerevisiae
In the yeast Saccharomyces cerevisiae, hexose transporter (Hxt) proteins transport glucose across the plasma membrane. The Hxt proteins are encoded by a multigene family with 20 members, of whichExpand
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Cation transport and growth regulation in neuroblastoma cells. Modulations of K+ transport and electrical membrane properties during the cell cycle
Cation transport and membrane potential were studied during the cell cycle of neuroblastoma cells (clone Neuro‐2A) to investigate the role of these parameters in growth regulation. The cells wereExpand
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