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Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies.
TLDR
Based on limited data, there was a suggestion that spreading dose over time (from a few days to > 1 year) may lower risk, possibly due to the opportunity for cellular repair mechanisms to operate. Expand
Second cancers among 40,576 testicular cancer patients: focus on long-term survivors.
TLDR
Testicular cancer survivors are at statistically significantly increased risk of solid tumors for at least 35 years after treatment, and young patients may experience high levels of risk as they reach older ages. Expand
Breast cancer following radiotherapy and chemotherapy among young women with Hodgkin disease.
TLDR
Hormonal stimulation appears important for the development of radiation-induced breast cancer, as evidenced by the reduced risk associated with ovarian damage from alkylating agents or radiation. Expand
Lung cancer following chemotherapy and radiotherapy for Hodgkin's disease.
TLDR
Past treatments with alkylating agents and radiation therapy for Hodgkin's disease were associated with an increased risk of lung cancer in a dose-dependent and additive fashion, but the precise risk estimates should be interpreted cautiously, given the possible residual and enhancing effects of tobacco. Expand
Tumors of the brain and nervous system after radiotherapy in childhood.
TLDR
It is confirmed that radiation doses on the order of 1 to 2 Gy can significantly increase the risk of neural tumors, and a strong dose--response relation was found. Expand
Risk of leukemia after chemotherapy and radiation treatment for breast cancer.
TLDR
Although leukemia occurs in few patients with breast cancer, significantly elevated risks were linked to treatments with regional radiation and alkylating agents, and melphalan is a more potent leukemogen than cyclophosphamide or radiotherapy. Expand
Solid cancers after bone marrow transplantation.
TLDR
The trend toward an increased risk over time after transplantation and the greater risk among younger patients indicate the need for life-long surveillance. Expand
Cellular telephones and cancer--a nationwide cohort study in Denmark.
TLDR
The results of this investigation, the first nationwide cancer incidence study of cellular phone users, do not support the hypothesis of an association between use of these telephones and tumors of the brain or salivary gland, leukemia, or other cancers. Expand
Study design and cohort characteristics of the Childhood Cancer Survivor Study: a multi-institutional collaborative project.
TLDR
The CCSS represents the largest and most extensively characterized cohort of childhood and adolescent cancer survivors in North America and serves as a resource for addressing important issues such as risk of second malignancies, endocrine and reproductive outcome, cardiopulmonary complications, and psychosocial implications, among this unique and ever-growing population. Expand
Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study.
TLDR
These studies demonstrated that women treated with pelvic irradiation and/or increasing alkylating agent doses were at risk for acute ovarian failure, premature menopause, and small-for-gestational-age offspring. Expand
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