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Gene Ontology: tool for the unification of biology
The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource
The Gene Ontology (GO) project provides structured, controlled vocabularies and classifications that cover several domains of molecular and cellular biology and are freely available for community use in the annotation of genes, gene products and sequences.
Gene Ontology Consortium: going forward
Improvements and expansions to several branches of the Gene Ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the research community are described.
Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii
The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome…
A promoter-level mammalian expression atlas
It is found that few genes are truly ‘housekeeping’, whereas many mammalian promoters are composite entities composed of several closely separated TSSs, with independent cell-type-specific expression profiles.
The Gene Ontology resource: enriching a GOld mine
A historical archive covering the past 15 years of GO data with a consistent format and file structure for both the ontology and annotations is made available to maintain consistency with other ontologies.
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.
The Mouse Genome Database (MGD): mouse biology and model systems
Improvements in MGD described here include the association of gene trap data with mouse genes and a new batch query capability for customized data access and retrieval.
Creating the gene ontology resource: design and implementation.
- J. Blake, J. Corradi, J. Eppig, D. Hill, J. Richardson, M. Ringwald
- Biology, Computer ScienceGenome research
The Gene Ontology project seeks to provide a set of structured vocabularies for specific biological domains that can be used to describe gene products in any organism, which includes building three extensive ontologies to describe molecular function, biological process, and cellular component.
Concept annotation in the CRAFT corpus
The concept annotations of the Colorado Richly Annotated Full-Text (CRAFT) Corpus have the potential to significantly advance biomedical text mining by providing a high-quality gold standard for NLP systems.