• Publications
  • Influence
Cellular oncogenes and retroviruses.
  • J. Bishop
  • Biology, Medicine
  • Annual review of biochemistry
  • 1983
Devoilement des oncogenes cellulaires: strategies experimentales et definitions. Caracteristiques structurales. Phylogenese. Expressions. Fonctions. Familles d'oncogenes cellulaires. Linkages.Expand
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Neurotrophin–3 is required for proper cerebellar development
Neurotrophin–3 (NT–3) is a member of the neurotrophin family, which includes nerve growth factor (NGF), brain–derived neurotrophic factor (BDNF) and neurotrophin–4/5 (NT–4/5). These factors areExpand
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Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia
The promyelocytic leukemia retinoic acid receptor α (PMLRARα) chimeric protein is associated with acute promyelocytic leukemia (APL). PMLRARα transgenic mice develop leukemia only after severalExpand
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Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable.
The most common chromosomal translocation in acute promyelocytic leukemia (APL), t15;17(q22;q21), creates PMLRARalpha and RARalphaPML fusion genes. We previously developed a mouse model of APL byExpand
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Oncogenes and proto-oncogenes.
  • J. Bishop
  • Medicine
  • Journal of cellular physiology. Supplement
  • 1 August 1983
The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanismsExpand
  • 12
Beta PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells.
BACKGROUND Platelet-derived growth factor (PDGF) promotes mitogenesis in fibroblast cell lines but stimulates neurite outgrowth in PC12 cells that ectopically express the beta PDGF receptor. ToExpand
  • 4
Exploring carcinogenesis with retroviral and cellular oncogenes.
  • J. Bishop
  • Medicine
  • Progress in medical virology. Fortschritte der…
  • 1985
  • 2
Enemies of Promise.
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