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- Publications
- Influence
Cellular oncogenes and retroviruses.
- J. Bishop
- Biology, Medicine
- Annual review of biochemistry
- 1983
Devoilement des oncogenes cellulaires: strategies experimentales et definitions. Caracteristiques structurales. Phylogenese. Expressions. Fonctions. Familles d'oncogenes cellulaires. Linkages.… Expand
Neurotrophin–3 is required for proper cerebellar development
- B. Bates, M. Rios, +4 authors R. Jaenisch
- Biology, Medicine
- Nature Neuroscience
- 1 February 1999
Neurotrophin–3 (NT–3) is a member of the neurotrophin family, which includes nerve growth factor (NGF), brain–derived neurotrophic factor (BDNF) and neurotrophin–4/5 (NT–4/5). These factors are… Expand
Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia
- S. Kogan, Diane E. Brown, +6 authors J. Bishop
- Biology, Medicine
- The Journal of experimental medicine
- 19 February 2001
The promyelocytic leukemia retinoic acid receptor α (PMLRARα) chimeric protein is associated with acute promyelocytic leukemia (APL). PMLRARα transgenic mice develop leukemia only after several… Expand
Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable.
- S. Kogan, S. H. Hong, D. B. Shultz, M. Privalsky, J. Bishop
- Biology, Medicine
- Blood
- 1 March 2000
The most common chromosomal translocation in acute promyelocytic leukemia (APL), t15;17(q22;q21), creates PMLRARalpha and RARalphaPML fusion genes. We previously developed a mouse model of APL by… Expand
Oncogenes and proto-oncogenes.
- J. Bishop
- Medicine
- Journal of cellular physiology. Supplement
- 1 August 1983
The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanisms… Expand
Beta PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells.
BACKGROUND
Platelet-derived growth factor (PDGF) promotes mitogenesis in fibroblast cell lines but stimulates neurite outgrowth in PC12 cells that ectopically express the beta PDGF receptor. To… Expand
Exploring carcinogenesis with retroviral and cellular oncogenes.
- J. Bishop
- Medicine
- Progress in medical virology. Fortschritte der…
- 1985