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Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.
TLDR
Postoperative concurrent administration of high-dose cisplatin with radiotherapy is more efficacious than radiotherapy alone in patients with locally advanced head and neck cancer and does not cause an undue number of late complications. Expand
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer.
TLDR
Induction chemotherapy with the addition of docetaxel significantly improved progression-free and overall survival in patients with unresectable squamous-cell carcinoma of the head and neck. Expand
Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial
TLDR
Immediate androgen suppression with an LHRH analogue given during and for 3 years after external irradiation improves disease-free and overall survival of patients with locally advanced prostate cancer. Expand
External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study.
TLDR
In patients with prostate cancer with high metastatic risk, immediate androgen suppression with an LHRH agonist given during and for 3 years after external irradiation improves 10-year disease-free and overall survival without increasing late cardiovascular toxicity. Expand
Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin.
TLDR
Adjuvant treatment with goserelin, when started simultaneously with external irradiation, improves local control and survival in patients with locally advanced prostate cancer. Expand
Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis
TLDR
Comparison of the different types of altered radiotherapy suggests that hyperfractionation has the greatest benefit, whereas the benefit on nodal control was less pronounced. Expand
Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)
In 2004, level I evidence was established for the postoperative adjuvant treatment of patients with selected high‐risk locally advanced head and neck cancers, with the publication of the results ofExpand
Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis
TLDR
The data indicate that even picomolar concentrations of gp120 prime T cells for activation-induced cell death are found, suggesting a mechanism for CD4+ T cell depletion in acquired immune deficiency syndrome (AIDS), particularly in the face of concurrent infection and antigenic challenge with other organisms. Expand
CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines.
TLDR
The objective of the present article is to present the consensus guidelines for the delineation of the node levels in the node-negative neck, and representative CTVs that are consistent with these guidelines are illustrated on CT sections. Expand
Critical impact of radiotherapy protocol compliance and quality in the treatment of advanced head and neck cancer: results from TROG 02.02.
TLDR
The critical importance of radiotherapy quality on outcome of chemoradiotherapy in head and neck cancer is demonstrated, with patients who received at least 60 Gy having a markedly inferior outcome. Expand
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