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A two-component regulatory system for self/non-self recognition in Ustilago maydis
In U. maydis the multiallelic b locus controls sexual and pathogenic development. In the b locus a gene coding for a regulatory protein had been identified, and it was suggested that the interactionExpand
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Excision of specific DNA-sequences from integrated retroviral vectors via site-specific recombination.
Vectors for gene transfer and gene therapy were developed which combine the advantages of the integrase and recombinase systems. This was achieved by inserting two loxP sites for specific DNAExpand
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P53-Dependent UVB Responsiveness of Human Keratinocytes Can Be Altered by Cultivation on Cell Cycle-arrested Dermal Fibroblasts
Abstract In cultured human keratinocytes, the tumor suppressor p53 acts as a control element in the protective response to UVB radiation and is affected by a variety of factors linked to cellularExpand
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Two different macronuclear EF-1 alpha-encoding genes of the ciliate Euplotes crassus are very dissimilar in their sequences, copy numbers and transcriptional activities.
Genes (EFA) encoding the translation elongation factor EF-1 alpha (EFA) or the prokaryotic homolog EFTu frequently occur in multiple copies in the same organism. This has been interpreted either inExpand
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Cloning of retroviral insertion sites possibly involved in growth-factor autonomy
A protocol has been established which allows obtaining growth-factor-independent cell mutants by retroviral insertion mutagenesis in vitro. In order to identify gene alterations possibly leading toExpand
P53‐Dependent UVB Responsiveness of Human Keratinocytes Can Be Altered by Cultivation on Cell Cycle‐arrested Dermal Fibroblasts
In cultured human keratinocytes, the tumor suppressor p53 acts as a control element in the protective response to UVB radiation and is affected by a variety of factors linked to cellular adhesion andExpand