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Contribution of the hyperpolarization-activated current (I(h)) to membrane potential and GABA release in hippocampal interneurons.
Intrinsic GABAergic interneurons provide inhibitory input to the principal neurons of the hippocampus. The majority of interneurons located in stratum oriens (s.o.) of the CA1 region express theExpand
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Regulation of the NMDA receptor by redox phenomena: inhibitory role of ascorbate
Redox phenomena seem to modulate activity of the N-methyl-D-aspartate receptor. Some reductants (ascorbate, hydroquinone) inhibit, while others (dithiothreitol, mercaptoethanol, penicillamine)Expand
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Clonidine attenuates increased brain glucose metabolism during naloxone-precipitated morphine withdrawal
The effect of two doses of clonidine on regional cerebral metabolic rates for glucose were measured during morphine withdrawal in rats. In the first study, 0 or 200 micrograms/kg clonidine wasExpand
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Co-treatment with MK-801 potentiates naloxone-precipitated morphine withdrawal in the isolated spinal cord of the neonatal rat.
The effects of acute and chronic administration of (MK-801: [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine hydrogen maleate) were assessed on morphine dependence in the isolatedExpand
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MK-801 blocks the expression but not the development of tolerance to morphine in the isolated spinal cord of the neonatal rat.
This study investigated the role of (MK-801; [(+)-5-methyl-10,11-dihydro-5 H-dibenzo[a,d]-cyclo-hepten-5,10-imine hydrogen maleate) in the development and expression of tolerance to morphine in theExpand
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Noradrenergic action of amphetamine following degeneration of descending monoaminergic fibers in the spinal cord
Amphetamine and methoxamine facilitated the flexor reflex in chronic spinal rats whose descending monoaminergic nerve endings were degenerated. Methoxamine, but not amphetamine, facilitated theExpand
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The influence of semicarbazide-induced depletion of -aminobutyric acid on presynaptic inhibition.
Summary Administration of semicarbazide to acute spinal cats resulted in a gradual and complete suppression of the dorsal root reflex and dorsal root potential. Semicarbazide also produced markedExpand
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The effect of the narcotic antagonists naloxone, naltrexone and nalorphine on spinal cord C-fiber reflexes evoked by electrical stimulation or radiant heat.
  • J. Bell, W. Martin
  • Chemistry, Medicine
  • European journal of pharmacology
  • 21 March 1977
C-fiber reflexes were recorded from an S1 ventral root in the acute decerebrate low spinal cat following stimulation of the ipsilateral superficial peroneal nerve or application of radiant heat toExpand
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Dissociation between amino-oxyacetic acid-induced depression of spinal reflexes and the rise in cord GABA levels.
Abstract Amino-oxyacetic acid (AOAA, 15–60 mg/kg produced a slow, dose-dependent depression of all segmentally evoked dorsal and ventral root activity in acute spinal cats. Amino-oxyacetic acid alsoExpand
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