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Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.
Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells.
Peroxiredoxin 2 and GAPDH are identified as two of the most oxidant-sensitive cell proteins and how readily peroxiredoxins undergo irreversible oxidation is highlighted.
Detection of oxidant sensitive thiol proteins by fluorescence labeling and two‐dimensional electrophoresis
A proteomic method to monitor the reduction and oxidation of protein thiols, and identify those thiol proteins most sensitive to oxidation is developed, valuable in elucidating redox signaling pathways.
The anti-cancer, anti-inflammatory and tuberculostatic activities of a series of 6,7-substituted-5,8-quinolinequinones.
Single-stranded RNA viruses infecting the invasive Argentine ant, Linepithema humile
New Zealand populations of the globally widely distributed invasive Argentine ant (Linepithema humile) are examined for RNA viruses and metatranscriptomic analysis identified six potential novel viruses in the Dicistroviridae family, which offer potential targets for biocontrol approaches.
The antiproliferative effects of phenoxodiol are associated with inhibition of plasma membrane electron transport in tumour cell lines and primary immune cells.
Proteomic detection of oxidized and reduced thiol proteins in cultured cells.
- S. Cuddihy, J. Baty, K. Brown, C. Winterbourn, M. Hampton
- Biology, Computer ScienceMethods in molecular biology
A method for fluorescent labelling of either reduced or oxidized thiols in combination with two-dimensional sodium dodecyl sulphate polyacrylamide gel electrophoresis (2DE) to detect changes in the redox proteome of cultured cells is described.
N,N-Bis(glycityl)amines as anti-cancer drugs.
The role of mitochondrial electron transport in tumorigenesis and metastasis.
The potential for a CRISPR gene drive to eradicate or suppress globally invasive social wasps
- P. J. Lester, M. Bulgarella, J. Baty, P. Dearden, J. Guhlin, J. Kean
- BiologyScientific Reports
- 24 July 2020
It is shown that different spermatogenesis genes have different levels of variation between introduced and native ranges, enabling a potential ‘precision drive’ that could target the reduced genetic diversity and genotypes within the invaded range.