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Randomised controlled trial of primary school based intervention to reduce risk factors for obesity
TLDR
Although it was successful in producing changes at school level, the programme had little effect on children's behaviour other than a modest increase in consumption of vegetables, which raises issues regarding the problems inherent in such trials. Expand
Evaluation of implementation and effect of primary school based intervention to reduce risk factors for obesity
TLDR
The programme was successful in producing school level changes to tackle risk factors for obesity and high levels of participation indicated support from schools, staff, parents, and pupils. Expand
Clinical manifestations and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians and Caucasians: is there a difference?
TLDR
A possible ethnic difference in the clinical and biochemical characteristics of South Asian vs. Caucasian women with PCOS is determined. Expand
The use of metformin for women with PCOS undergoing IVF treatment.
TLDR
Short-term co-treatment with metformin for patients with PCOS undergoing IVF/ICSI cycles does not improve the response to stimulation but significantly improves the pregnancy outcome and reduces the risk of OHSS. Expand
Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data.
TLDR
Evidence is provided to support the view that vitamin D and VDR may have a small but potentially important role in melanoma susceptibility, and putatively a greater role in disease progression. Expand
Children's Residential Weight-Loss Programs Can Work: A Prospective Cohort Study of Short-Term Outcomes for Overweight and Obese Children
TLDR
In the short term at least, this weight- loss program was effective across a range of health outcomes and future research should investigate whether benefits can be generalized across weight-loss camps and how the intervention can be adapted to nonresidential, term-time settings. Expand
Heart-type fatty acid-binding protein predicts long-term mortality and re-infarction in consecutive patients with suspected acute coronary syndrome who are troponin-negative.
TLDR
It is demonstrated that the prognostic value of elevated H-FABP is additive to troponin in low- and intermediate-risk patients with suspected ACS, and other studies suggest that the observations reflect the value of H- FABP as a marker of myocardial ischemia, even in the absence of frank necrosis. Expand
Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study.
TLDR
Weight loss alone through lifestyle changes improves menstrual frequency andLogistic regression analysis was used to analyse the independent variables (metformin, percentage of weight loss, initial BMI and age) to predict the improvement of menses. Expand
Interference in immunoassay is an underestimated problem
TLDR
Clinical laboratories should be alert to assay interference from antibodies irrespective of its nature, as immunoassays will remain an indispensable analytical tool, unlikely to be replaced in the foreseeable future by a practical alternative. Expand
Troponin-I concentration 72 h after myocardial infarction correlates with infarct size and presence of microvascular obstruction
TLDR
A single measurement of 72-h troponin-I is similar to serial CK measurements in the estimation of both myocardial infarct size and extent of MVO, and is superior to 12-h Tropon in-I measurements. Expand
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