Skip to search formSkip to main contentSkip to account menu
Classic and Golli Myelin Basic Protein have distinct developmental trajectories in human visual cortex
TLDR
The unique pattern of Golli-MBP expression across the lifespan suggests that it supports high levels of neuroimmune interaction in cortical development and in aging.
View on PubMed
A direct interareal feedback-to-feedforward circuit in primate visual cortex
TLDR
Using viral-mediated monosynaptic circuit tracing in macaque visual cortex, it is found that neurons sending FF projections to a higher-level area receive monosyneaptic FB inputs exclusively from that area, and FB can rapidly and selectively influence the activity of incoming FF signals.
View on PubMed
Experience-dependent central vision deficits: Neurobiology and visual acuity
View on Elsevier
A high-throughput semi-automated preparation for filtered synaptoneurosomes
View on Elsevier
Classification of Visual Cortex Plasticity Phenotypes following Treatment for Amblyopia.
TLDR
Cluster analysis of the plasticity phenotypes suggests that BV supports adaptive plasticity while RO and BD promote a maladaptive pattern, and that balancing Hebbian (GluN2A) and homeostatic mechanisms is necessary for the recovery of vision.
View on PubMed
Classification of Visual Cortex Plasticity Phenotypes following Treatment for Amblyopia
TLDR
Cluster analysis of the plasticity phenotypes suggests that BV supports adaptive plasticity while RO and BD promote a maladaptive pattern, and that balancing Hebbian (GluN2A) and homeostatic mechanisms is necessary for the recovery of vision.
View via Publisher
A primer on high-dimensional data analysis workflows for studying visual cortex development and plasticity
TLDR
A new approach for identifying high-dimensional features and using them to construct a plasticity phenotype that identifies neurobiological differences among clusters is described and an R package “v1hdexplorer” is included that aggregates the various coding packages and custom visualization scripts written in R Studio.
View via Publisher
Corrigendum: A Practical Guide to Sparse k-Means Clustering for Studying Molecular Development of the Human Brain
[This corrects the article DOI: 10.3389/fnins.2021.668293.].
View on PubMed
Constructing plasticity phenotypes to classify experience-dependent development of the visual cortex
TLDR
This work has developed an approach for studying V1 plasticity that takes advantage of the known functions of many synaptic proteins for regulating visual plasticity and using that to rebrand the results of high-dimensional analyses into a plasticity phenotype.
View via Publisher
Protocol for a High-Throughput Semiautomated Preparation for Filtered Synaptoneurosomes
View via Publisher
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License