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Consensus statement on concussion in sport—the 5th international conference on concussion in sport held in Berlin, October 2016
This document is developed for physicians and healthcare providers who are involved in athlete care, whether at a recreational, elite or professional level, and provides an overview of issues that may be of importance to healthcare providers involved in the management of SRC.
Association between Recurrent Concussion and Late-Life Cognitive Impairment in Retired Professional Football Players
The findings suggest that the onset of dementia-related syndromes may be initiated by repetitive cerebral concussions in professionalFootball players, and an earlier onset of Alzheimer's disease in the retirees than in the general American male population.
Recurrent concussion and risk of depression in retired professional football players.
The findings suggest a possible link between recurrent sport-related concussion and increased risk of clinical depression and emphasize the importance of understanding potential neurological consequences of recurrent concussion.
Role of subconcussion in repetitive mild traumatic brain injury.
- J. Bailes, A. L. Petraglia, B. Omalu, E. Nauman, T. Talavage
- PsychologyJournal of neurosurgery
- 1 November 2013
The authors propose "subconcussion" as a significant emerging concept requiring thorough consideration of the potential role it plays in accruing sufficient anatomical and/or physiological damage in athletes and military personnel, such that the effects of these injuries are clinically expressed either contemporaneously or later in life.
Emerging Histomorphologic Phenotypes of Chronic Traumatic Encephalopathy in American Athletes
The emerging histomorphologic features of the CTE cohort may specify histologic criteria for CTE diagnosis, may identify emerging histologic variants of CTE and may facilitate more objective surveillance and accurate identification of sentinel CTE cases.
Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide.
This case is reported as a sentinel case of CTE in an Iraqi war veteran diagnosed with PTSD to possibly stimulate new lines of thought and research in the possible pathoetiology and pathogenesis of PTSD in military veterans as part of the CTE spectrum of diseases, and as chronic sequelae and outcomes of repetitive traumatic brain injuries.
Chronic traumatic encephalopathy (CTE) in a National Football League Player: Case report and emerging medicolegal practice questions
- B. Omalu, R. Hamilton, I. Kamboh, S. DeKosky, J. Bailes
- Medicine, PsychologyJournal of forensic nursing
- 1 March 2010
This 44‐year‐old retired NFL player manifested a premortem history of cognitive and neuropsychiatric impairment, which included in part, chronic depression, suicide attempts, insomnia, paranoia, and impaired memory before he finally committed suicide, with autopsy findings, apolipoprotein E genotype, and brain tissue evidence of chronic brain damage.
A systematic review of potential long-term effects of sport-related concussion
- G. Manley, A. Gardner, G. Iverson
- Psychology, MedicineBritish Journal of Sports Medicine
- 28 April 2017
More research is needed to better understand the prevalence of chronic traumatic encephalopathy and other neurological conditions and diseases, and the extent to which they are related to concussions and/or repetitive neurotrauma sustained in sports.
In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging
- J. Barrio, G. Small, V. Kepe
- Psychology, BiologyProceedings of the National Academy of Sciences
- 6 April 2015
This new work shows how a tau-sensitive brain imaging agent, [F-18]FDDNP, may be able to detect the disease in living people with varying degrees of symptoms of chronic traumatic encephalopathy, and suggests the presence of neuropathological patterns consistent with models of concussion.
An overview of the basic science of concussion and subconcussion: where we are and where we are going.
The forces behind the primary phase of injury in mild TBI, as well as the immediate and delayed cellular events responsible for the secondary phase of Injury leading to neuronal dysfunction and possible cell death are reviewed.