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Assessing the root of bilaterian animals with scalable phylogenomic methods
  • A. Hejnol, M. Obst, +14 authors C. Dunn
  • Biology, Medicine
  • Proceedings of the Royal Society B: Biological…
  • 22 December 2009
New sequence data and methods strongly uphold previous suggestions that Acoelomorpha is sister clade to all other bilaterian animals, find diminishing evidence for the placement of the enigmatic Xenoturbella within Deuterostomia, and place Cycliophora with Entoprocta and EctoproCTa. Expand
Acoel flatworms: earliest extant bilaterian Metazoans, not members of Platyhelminthes.
Sequence data of 18S ribosomal DNA genes from non-fast evolving species of acoels and other metazoans reveal that this group does not belong to the Platyhelminthes but represents the extant members of the earliest divergent Bilateria, an interpretation that is supported by recent studies on the embryonic cleavage pattern and nervous system of acOels. Expand
First molecular evidence for the existence of a Tardigrada + Arthropoda clade.
The results obtained represent the first molecular evidence for a Tardigrada + Arthropoda clade and indicate the need to review those obtained solely on morphological characters. Expand
Are the Platyhelminthes a monophyletic primitive group? An assessment using 18S rDNA sequences.
It is suggested that parasitic platyhelminthes appeared early in the evolution of the group and form a sister group to a still-unresolved clade made by Nemertodermatida, Lecithoepitheliata, Prolecithophora, Proseriata and Rhabdocoela, and that Seriata is paraphyletic. Expand
Mitosis in the intact and regenerating planarian Dugesia mediterranea n.sp. I. Mitotic studies during growth, feeding and starvation
Planarian neoblasts, the only cell type in this organism endowed with mitotic power, decrease in density as total body volume, total cell number, and length increase. Studies on mitosis show that theExpand
Lophotrochozoa internal phylogeny: new insights from an up-to-date analysis of nuclear ribosomal genes
Ribosomal RNA genes are considered a reliable source for the study of deep divergences in the metazoan tree, provided that the data are treated carefully and the LBA effect is minimized. Expand
JNK signaling pathway required for wound healing in regenerating Drosophila wing imaginal discs.
A role for the JNK pathway in imaginal disc wound healing, similar to that reported for other healing processes such as embryonic dorsal closure, thoracic closure, and adult epithelial wound healing in Drosophila, is demonstrated. Expand
Spatial distribution and differentiation potential of stem cells in hatchlings and adults in the marine platyhelminth macrostomum sp.: a bromodeoxyuridine analysis.
The idea of platyhelminth neoblasts as an unparalleled stem-cell system within the Animal Kingdom calling for further investigation is strengthened. Expand
A phylogenetic analysis of myosin heavy chain type II sequences corroborates that Acoela and Nemertodermatida are basal bilaterians
This study demonstrates that Platyhelminthes are polyphyletic and that acoels and nemertodermatids are the extant earliest bilaterians, and that the common bilaterian ancestor was not, as currently held, large and complex but small, simple, and likely with direct development. Expand
Quantitative analysis of cell types during growth, degrowth and regeneration in the planarians Dugesia mediterranea and Dugesia tigrina
A method of tissue maceration (dissociation) of planarian tissues into single cells was used to characterize the basic cell types in the planarians Dugesia mediterranea and Dugesia tigrina, and toExpand