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Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila
TLDR
It is shown that the intestinal homeobox gene Caudal regulates the commensal-gut mutualism by repressing nuclear factor kappa B–dependent antimicrobial peptide genes, and reveals that a specific genetic deficiency within a host can profoundly influence the gut commensAL microbial community and host physiology. Expand
An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice
TLDR
Modulation of the gut microbiota (by an increase in the Akkermansia spp. population) may contribute to the antidiabetic effects of metformin, thereby providing a new mechanism for the therapeutic effect of met formin in patients with T2D. Expand
Diversity of ammonium-oxidizing bacteria in a granular sludge anaerobic ammonium-oxidizing (anammox) reactor.
TLDR
The quantitative results from real-time polymerase chain reaction (PCR) amplification showed that the dominant AnAOB comprised approximately 50% of the total bacterial 16S rRNA genes in the reactor, whereas the AAOB of beta-Proteobacteria represented only about 3%. Expand
Insect Gut Bacterial Diversity Determined by Environmental Habitat, Diet, Developmental Stage, and Phylogeny of Host
TLDR
This insect-order-spanning investigation of the gut microbiota provides insights into the relationships between insects and their gut bacterial communities. Expand
Proteobacteria: microbial signature of dysbiosis in gut microbiota.
TLDR
This work reviews studies that explored the association between an abnormal expansion of Proteobacteria and a compromised ability to maintain a balanced gut microbial community and proposes that an increased prevalence of ProTeobacteria is a potential diagnostic signature of dysbiosis and risk of disease. Expand
Metagenomic Analysis of Kimchi, a Traditional Korean Fermented Food
TLDR
In this study, metagenomic approaches were used to monitor changes in bacterial populations, metabolic potential, and overall genetic features of the microbial community during the 29-day fermentation process of Kimchi, and provide insights into the kimchi microbial community. Expand
Diversity and Abundance of Single-Stranded DNA Viruses in Human Feces
TLDR
A phylogenetic analysis of 24 large contigs of microphages based on conserved capsid protein sequences revealed five distinct newly discovered evolutionary microphage groups that were distantly related to previously knownMicrophages, suggesting that Bacteroides and Prevotella are the sources of infecting microPHages in their hosts. Expand
Comparative Analysis of Korean Human Gut Microbiota by Barcoded Pyrosequencing
TLDR
UPGMA cluster analysis showed that the species composition of gut microbiota was host-specific and stable over the duration of the test period, but the relative abundance of each member fluctuated, suggesting that gut microbial composition is related to internal and external characteristics of each country member such as host genetics and diet styles. Expand
Bacterial community analysis during fermentation of ten representative kinds of kimchi with barcoded pyrosequencing.
TLDR
It was found that bacterial communities differed between starter-inoculated and non- inoculated kimchi at the early stages of fermentation, but overall there were no significant differences in the late phases. Expand
Investigation of archaeal and bacterial diversity in fermented seafood using barcoded pyrosequencing
TLDR
The results indicate that the archaeal populations in the fermented seafood analyzed are diverse and include the halophilic and mesophilic groups, and that barcoded pyrosequencing is a promising and cost-effective method for analyzing microbial diversity compared with conventional approaches. Expand
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