J. B. Wright

Publications34
h-index14
Citations811
Highly Influential Citations8
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The chemistry of the benzimidazoles.
Inhibition of allergic reactions by cromoglycate and by a new antiallergy drug U-42,585E. II. Activity in primates against aerosolized Ascaris suum antigen.
TLDR
Two parameters used to measure lung function, respiratory rate increase and tidal volume decrease, were significantly altered in a dose-related fashion by U-42,585E when the latter was administered either by the intravenous, intrabronchial, or the oral route. Expand
ANTIDIABETIC AGENTS. N4-ARYLSULFONYLSEMICARBAZIDES.
THE ANTIDIABETIC ACTIVITY OF 3,5-DIMETHYLPYRAZOLES.
Computational Investigation of the Solvation of Nitric Acid: Formation of the NO3 - and H3O + Ion Pair
MP2 and B3LYP calculations were performed to investigate complexes of nitric acid with water using the 6?311++G(2d,p) basis set were used to determine optimized geometries and binding energies for… Expand
Fragmentation of an alkali metal-attached peptide probed by collision-induced dissociation fourier transform mass spectrometry and computational methodology.
TLDR
It is concluded that metal coordination plays a key role in guiding the gas-phase fragmentation of the cationized peptide. Expand
Inhibition of allergic reactions by cromoglycate and by a new anti-allergy drug U-42,585E. I. Activity in rats.
TLDR
A new inhibitor of IgE-mediated allergic reactions has been studied in rats and its ability to inhibit ionophore-induced 45Ca++ flux correlates well with inhibition of histamine release. Expand
N,N'-(Phenylene)dioxamic acids and their esters as antiallergy agents.
A series of dialkyl N,N'-(m-phenylene)dioxamates was synthesized by treatment of the requisite m-phenylenediamines with an alkyloxalyl chloride in the presence of triethylamine. Hydrolysis with… Expand
Quinoline derivatives as antiallergy agents.
Quantum mechanics and mixed quantum mechanics/molecular mechanics simulations of model nerve agents with acetylcholinesterase
Abstract. The accurate modeling of biological processes presents major computational difficulties owing to the inherent complexity of the macromolecular systems of interest. Simulations of… Expand
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