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Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
- D. Brat, Roel G. W. Verhaak, +304 authors J. Zhang
- Biology, Medicine
- The New England journal of medicine
- 25 June 2015
BACKGROUND Diffuse low-grade and intermediate-grade gliomas (which together make up the lower-grade gliomas, World Health Organization grades II and III) have highly variable clinical behavior that… Expand
Local disease control after decompressive surgery and adjuvant high-dose single-fraction radiosurgery for spine metastases.
OBJECT Adjuvant radiation following epidural spinal cord decompression for tumor is a powerful tool used to achieve local disease control and preserve neurological function. To the authors'… Expand
Radiosurgery for the Treatment of Recurrent Central Neurocytomas
OBJECTIVECentral neurocytomas are benign neoplasms with neuronal differentiation typically located in the lateral ventricles of young adults. Although the treatment of choice is complete surgical… Expand
Primary intraosseous meningioma.
Primary intraosseous meningiomas are a subtype of primary extradural meningiomas and constitute fewer than 2% of meningiomas overall, but they represent approximately two thirds of all extradural… Expand
Effect of dextran-induced changes in refractive index and aggregation on optical properties of whole blood.
- Xiangqun Xu, R. Wang, J. B. Elder, V. Tuchin
- Materials Science, Medicine
- Physics in medicine and biology
- 7 May 2003
The purpose of the present study is to investigate systematically the mechanisms of alterations in the optical properties of whole blood immersed in the biocompatible agent dextran, and to define the… Expand
The human glutathione S-transferases: a case-control study of the incidence of the GST1 0 phenotype in patients with adenocarcinoma.
The suggestion that individuals with the GST1 0 phenotype have a greater susceptibility to carcinogens than those with other GST1 phenotypes has been examined by using a starch gel zymogram approach… Expand
LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential
- C. Hong, Winson S. Ho, C. Zhang, C. Yang, J. B. Elder, Z. Zhuang
- Biology, Medicine
- Cancer biology & therapy
- 21 April 2015
Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that plays a significant role in mitotic progression and cellular responses to DNA damage. While traditionally viewed as a tumor… Expand
Propylene glycol as a contrasting agent for optical coherence tomography to image gastrointestinal tissues
Optical coherence tomography (OCT) is a recently developed imaging technique that has the potential to advance the early diagnosis of diseases in the human gastrointestinal (GI) tract. How ever, the… Expand
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Summary Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer… Expand
ABERRANT ANGIOGENIC CHARACTERISTICS OF HUMAN BRAIN ARTERIOVENOUS MALFORMATION ENDOTHELIAL CELLS
OBJECTIVETo identify and characterize the phenotypic and functional differences of endothelial cells derived from cerebral arteriovenous malformations (AVM), as compared with endothelial cells… Expand