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The genome sequence of Rickettsia prowazekii and the origin of mitochondria
The complete genome sequence of the obligate intracellular parasite Rickettsia prowazekii, the causative agent of epidemic typhus, is described, which contains 834 protein-coding genes and is more closely related to mitochondria than is any other microbe studied so far.
Lateral gene transfer in eukaryotes
- J. Andersson
- BiologyCellular and Molecular Life Sciences CMLS
- 9 March 2005
Findings in this work indicate that lateral gene transfer frequently occurs in protists with phagotrophic lifestyles, possibly with rates comparable to prokaryotic organisms, and have implications for eukaryotic genomic research in general, and studies of the origin and phylogeny of eucaryotes in particular.
Draft Genome Sequencing of Giardia intestinalis Assemblage B Isolate GS: Is Human Giardiasis Caused by Two Different Species?
The genomic differences between WB and GS may explain some of the observed biological and clinical differences between the two isolates, and it suggests that assemblage A and B Giardia can be two different species.
Multilocus Genotyping of Human Giardia Isolates Suggests Limited Zoonotic Transmission and Association between Assemblage B and Flatulence in Children
This study shows that certain assemblage A subtypes are potentially zoonotic and that flatulence is connected to assemblages B infections in young children and can be a valuable tool in outbreak situations and to help identify possibleZoonotic transmission.
From mouse to moose: multilocus genotyping of Giardia isolates from various animal species.
Phylogenetic Analyses of Diplomonad Genes Reveal Frequent Lateral Gene Transfers Affecting Eukaryotes
Genome degradation is an ongoing process in Rickettsia.
The results strongly suggest that there is a high spontaneous rate of deletions as well as a strong mutation bias toward AT pairs in the Rickettsia genomes.
Dominance of Giardia assemblage B in León, Nicaragua.
Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate
Compared genomics of the three diverse Giardia intestinalis isolates P15, GS and WB to define a core proteome for this species complex and to identify lineage-specific genes were used to identify novel members of the VSP, NEK Kinase and HCMP gene families.