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Inhalation studies with benzo[a]pyrene in Syrian golden hamsters.
Groups of Syrian golden hamsters were exposed by inhalation to benzo[a]pyrene (BP) in concentrations of 2.2, 9.5, and 45.6 mg/m3 air. Although 45.6 mg BP/m3 air was carcinogenic and toxic, 2.2 mgExpand
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Spontaneous tumors and common diseases in three types of hamsters.
Hamsters of three types designated as inbred cream (Epp/e/e), linebred white (EPP/cdcd/RB/A), and linebred albino (EPP/cdcde/e) were thoroughly examined histopathologically for spontaneous diseases.Expand
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Spontaneous tumors and common diseases in two colonies of Syrian hamsters. II. Respiratory tract and digestive system.
Spontaneous respiratory tract neoplasms in Syrian hamsters occurred in almost equal frequencies in two colonies: 3% in the Eppley Colony (EC) and 3.6% in the Hannover Colony (HC). Neoplasms were inExpand
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Effects of age and gender on fat-induced gallbladder contraction and gastric emptying of a caloric liquid meal: a sonographic study.
In this study, the gastric emptying of a liquid fatty meal and the consecutive gallbladder contraction were simultaneously measured by ultrasound in four different age- and sex-related groups ofExpand
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A potent pancreatic carcinogen in Syrian hamsters: N-nitrosobis(2-oxopropyl)amine.
N-Nitrosobis(2-oxopropyl)amine (BOP), a further postulated beta-metabolite of di-n-propylnitrosamine, induced a high incidence of pancreatic duct adenomas and adenocarcinomas as early as 13 weeks inExpand
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Tumorigenesis in the nasal olfactory region of Syrian golden hamsters as a result of di-n-propylnitrosamine and related compounds.
The morphology of neoplasms in the nasal olfactory region of the Syrian golden hamster observed after s.c. injections of di- n -propylnitrosamine, β-hydroxypropyl- n -propylnitrosamine, β-oxopropyl-Expand
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A chronic study of artificial sweeteners in Syrian golden hamsters.
Chronic administration of saccharin and sodium or calcium cyclamates in drinking water to Syrian golden hamsters, up the maximum tolerated dose level, failed to induce an excess of tumors compared toExpand
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Spontaneous tumors and common diseases in two colonies of Syrian hamsters. III. Urogenital system and endocrine glands.
The frequency of spontaneously occuring neoplasms in the urogenital system and endocrine organs was examined in two Syrian hamster colonies [Eppley colony (EC); Hannover colony (HC)]. With theExpand
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Pancreatic neoplasms in an animal model: Morphological, biological, and comparative studies
After a short latency (15 weeks), a 100% incidence of pancreatic neoplasms was induced in Syrian golden hamsters, following the administration of 2,2′‐dihydroxy‐di‐n‐propylnitrosamine (DHPN). DataExpand
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Early lesions of pancreatic ductal carcinoma in the hamster model.
Syrian golden hamsters were treated weekly with 10 mg/kg body weight N-nitrosobis (2-oxopropyl) amine for life (Group 1) or 6 weeks and were sacrificed at biweekly intervals from 2 weeks (Group 1)Expand
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