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Alternative approach to the preparation of chitosan beads
Abstract A controlled-release protein delivery system was investigated by using bovine serum albumin (BSA) as a model drug. Chitosan was reacted with sodium alginate in the presence of… Expand
Release characteristics of chitosan treated alginate beads: II. Sustained release of a low molecular drug from chitosan treated alginate beads.
It appeared that chitosan treated alginate beads may be used for a potential controlled release system of small molecular drugs with high solubility, instead of alginated beads. Expand
Preparation of fucoidan-chitosan hydrogel and its application as burn healing accelerator on rabbits.
- A. Sezer, E. Cevher, F. Hatipoglu, Z. Oğurtan, A. L. Baş, J. Akbuǧa
- Chemistry, Medicine
- Biological & pharmaceutical bulletin
- 1 December 2008
The best regeneration on dermal papillary formation and the fastest closure of the wounds were observed in fucoidan-chitosan hydrogels after 14 d treatment, and the adhesiveness of hydrogel increased with the polymer concentration. Expand
Preparation and evaluation of cross-linked chitosan microspheres containing furosemide
Abstract Chitosan microspheres containing furosemide were prepared from a w/o emulsion system using liquid paraffin as the external phase and a solution of chitosan in acetic acid as the disperse… Expand
Chitosan beads for the delivery of salmon calcitonin : preparation and release characteristics
Abstract Salmon calcitonin (sCT)-loaded chitosan beads were prepared by dropping a drug containing solution of chitosan into tripolyphosphate solution. The droplets instantaneously formed gelled… Expand
Release characteristics of chitosan treated alginate beads: I. Sustained release of a macromolecular drug from chitosan treated alginate beads.
It is proposed that chitosan treated alginate beads may be used as a potential controlled release system of such macromolecules. Expand
Controlled release of interleukin-2 from chitosan microspheres.
It can be said that chitosan microsphere is a suitable carrier for rIL-2 delivery, as it remained biologically active and could be completely recovered from the release medium. Expand
Co-encapsulation of two plasmids in chitosan microspheres as a non-viral gene delivery vehicle.
- S. Ozbaş-Turan, C. Aral, L. Kabasakal, M. Keyer-Uysal, J. Akbuǧa
- Chemistry, Medicine
- Journal of pharmacy & pharmaceutical sciences : a…
The results showed that two plasmids could be encapsulated in chitosan microspheres without affecting their structural and functional integrity and sustained and high protein production was obtained with thesemicrospheres. Expand
Fucosphere—New microsphere carriers for peptide and protein delivery: Preparation and in vitro characterization
The extent of drug release from the microspheres was dependent on the concentrations of polymers and BSA, chitosan origin and type of preparation method, and this new fucoidan microsphere system may be a potential delivery of macromolecular drug such as peptide and protein. Expand
The Preparation and Stability of Fast Release Furosemide – PVP Solid Dispersion
AbstractFurosemide-PVP solid dispersion systems were prepared by co-evaporation and freeze-drying methods. The X-ray diffraction patterns indicated that furosemide in the coprecipitates was in… Expand