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Antimalarial mixed ligand metal complexes: Synthesis, physicochemical and biological activities
Complexation behaviour of mixed complexes of mefloquine hydrochloride and chloroquine phosphate (first-line antimalarial drugs) with Cobalt(II), Nickel(II) and Iron(III) were studied; the complexes… Expand
Biological activities of some Fluoroquinolones-metal complexes
Background : Metal ions play a vital role in the design of more biologically active drugs. Aim : The paper reviewed the antimicrobial, toxicological and DNA cleavage studies of some synthesized metal… Expand
Synthesis and Biological Activities on Metal Complexes of 2,5-Diamino-1,3,4-thiadiazole Derived from Semicarbazide Hydrochloride
A bioactive ligand, 2,5-diamino-1,3,4-thiadiazole (L), derived from semicarbazide hydrochloride, and its metal complexes were prepared and characterized. The complexes were characterized using… Expand
Iron(III) and copper(II) complexes bearing 8-quinolinol with amino-acids mixed ligands: Synthesis, characterization and antibacterial investigation
Abstract Four d-orbital metal complexes with mixed ligands derived from 8-hydroxyquinoline (HQ) and amino acids (AA): l -alanine and methionine have been synthesized through a mild reflux in alkaline… Expand
Synthesis, Toxicological and Antimicrobial Activities of Mn (II) and Fe(III) with N- and S-donor Ligand
Removal of Pb2+ and Cr6+ ions from aqueous solution by earthworm cast soil.
The problem of removing pollutants from aqueous wastewater is growing with the increase in water pollution owing to enhanced industrial activities. Three earthworm cast soil types were studied.… Expand
Synthesis, antimicrobial potential and toxicological activities of Ni(II) complex of mefloquine hydrochloride
Transition metal complex of Ni(II) with mefloquine hydrochloride (antimalaria drug) was synthesized using a template method. Chemical analysis including conductivity measurements and spectroscopic… Expand
Ligation of Fe(III) and Mn(II) Complexes by Bithiourea and Their Biological Activity
- J. Adediji, S. A. Amolegbe, S. Adewuyi, C. A. Akinremi, Y. C. Oyeniran, B. Afolayan
- 2 June 2013
Complexes of Fe(III) and Mn(II) with bithiourea were synthesized and characterised by elemental analysis, magnetic measurements, infrared spectroscopy, UV/visible, thin layer chromatography, and… Expand
Antimalarial, Antimicrobial, and Acute Toxicity Activities of Mefloquine-Pyrimethamine Metal Complex.
As part of our contribution to the on-going studies in developing a new and effective antimalarial drug. Complexation behavior of mixed Mefloquine (Mef) and Pyrimethamine (Pyr) [Antimalarial drug]… Expand
Synthesis and Antitubercular Activities of Cu(II) Metal Complexes with some Semicarbazide Derivatives.
The emergence of new cases, the increased incidence of multi-drug resistant strains of Mycobacterium tuberculosis, and the adverse effects of first- and second-line antituberculosis drugs has led to… Expand