Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases
- G. Garcia‐Tsao, J. Abraldes, A. Berzigotti, J. Bosch
- MedicineHepatology
- 1 January 2017
Treatment of etiology, by ameliorating cyanoacrylate injection and endovascular approach, target the mechanical component of the increased intrahepatic resistance, which leads to a hyperdynamic circulatory state that further increases portal venous inflow and PP.
Early use of TIPS in patients with cirrhosis and variceal bleeding.
- J. García‐Pagán, K. Caca, J. Bosch
- MedicineNew England Journal of Medicine
- 24 June 2010
In patients with cirrhosis who were hospitalized for acute variceal bleeding and at high risk for treatment failure, the early use of TIPS was associated with significant reductions in treatment failure and in mortality.
The clinical use of HVPG measurements in chronic liver disease
- J. Bosch, J. Abraldes, A. Berzigotti, J. García‐Pagán
- Medicine, BiologyNature Reviews Gastroenterology &Hepatology
- 1 September 2009
The main clinical applications for HVPG include diagnosis, risk stratification, identification of patients with hepatocellular carcinoma who are candidates for liver resection, monitoring of the efficacy of medical treatment, and assessment of progression of portal hypertension.
Current management of portal hypertension.
- J. Bosch, J. Abraldes, R. Groszmann
- MedicineJournal of Hepatology
- 2003
Elastography, spleen size, and platelet count identify portal hypertension in patients with compensated cirrhosis.
- A. Berzigotti, S. Seijo, J. Bosch
- MedicineGastroenterology
- 2013
Combined data on LS, spleen diameter, and platelet count can be used to identify patients with compensated cirrhosis most likely to have CSPH and EV.
Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis
- J. Michelena, J. Altamirano, R. Bataller
- Medicine, BiologyHepatology
- 1 September 2015
In the presence or absence of infections, SIRS is a major determinant of MOF and mortality in AH, and the mechanisms involved in the development of SirS should be investigated; procalcitonin serum levels can help to identify patients with infection, and lipopolysaccharide levels may help to predict mortality and the response to steroids.
A histologic scoring system for prognosis of patients with alcoholic hepatitis.
- J. Altamirano, R. Miquel, R. Bataller
- MedicineGastroenterology
- 1 May 2014
A histologic scoring system to predict short-term mortality of patients with alcoholic hepatitis (AH) and developed a patient classification system that might be used in clinical decision making are developed.
Good long‐term outcome of Budd‐Chiari syndrome with a step‐wise management
- S. Seijo, A. Plessier, J. García‐Pagán
- MedicineHepatology
- 1 May 2013
The current study confirms, in a large cohort of patients with BCS recruited over a short period, that a step‐wise treatment approach provides good long‐term survival and validates the Rotterdam score for predicting intervention‐free survival and the BCS‐TIPS PI score for predicted survival.
Improved clinical outcome using polytetrafluoroethylene-coated stents for TIPS: results of a randomized study.
- C. Bureau, J. García‐Pagán, J. Vinel
- MedicineGastroenterology
- 1 February 2004
The use of polytetrafluoroethylene-covered prostheses improves transjugular intrahepatic portosystemic shunt patency and decreases the number of clinical relapses and reinterventions without increasing the risk of encephalopathy.
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