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Mesoporous silica nanocarriers encapsulated antimalarials with high therapeutic performance
The use of nanocarriers in drug delivery is a breakeven research and has received a clarion call in biomedicine globally. Herein, two newly nano-biomaterials: MCM-41 encapsulated quinine (MCM-41 ⊃Expand
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Biological activities of some Fluoroquinolones-metal complexes
Background : Metal ions play a vital role in the design of more biologically active drugs. Aim : The paper reviewed the antimicrobial, toxicological and DNA cleavage studies of some synthesized metalExpand
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Synthesis and biological studies of Co(II) and Cd( II) 5-(3,4,5- trimethoxybenzyl) pyrimidine-2,4-diamine (Trimethoprim) complexes
Two metal complexes of Co(II) and Cd(II) 5-(3,4,5-trimethoxybenzyl) pyrimidine-2,4-diamine (Trimethoprim) were synthesized and characterized by both analytical and spectroscopic methods. They areExpand
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Cu(II) and Fe(III) complexes of sulphadoxine mixed with pyramethamine: Synthesis, characterization, antimicrobial and toxicology study
Two new mixed ligands metal complexes of sulphadoxine and pyramethamine were prepared by using CuCl2.6H2O and FeCl3.6H2O. The complexes were characterized by elemental analysis, melting pointExpand
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Some Metal-Antimalarial Drug Complexes: Synthesis, Characterization and their Effect Against Malaria Parasites
A series of metal complexes of Sulfadoxine-Pyrimethamine (SP) have been synthesized and characterized. The crystal structures have been determined by spectroscopic techniques using Infra Red (l R),Expand
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Synthesis and Biological Activities on Metal Complexes of 2,5-Diamino-1,3,4-thiadiazole Derived from Semicarbazide Hydrochloride
A bioactive ligand, 2,5-diamino-1,3,4-thiadiazole (L), derived from semicarbazide hydrochloride, and its metal complexes were prepared and characterized. The complexes were characterized usingExpand
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Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases
Metal coordination of bioorganic compounds from both natural and synthetic products is not only gaining recognition in drug design and medicinal inorganic chemistry research, also they are beingExpand
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Toxicological studies and antimicrobial properties of some Iron ( III ) complexes of Ciprofloxacin
Two iron(III) complexes of Ciprofloxacin were synthesized by reaction of the ligand with iron(III) chloride hexahydrate in different solutions. The nature of bonding of the ligands and the structureExpand
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Copper(II) Complexes of 4, 4- Diaminodiphenylsulphone: Synthesis, Characterization and Biological Studies
Five complexes of copper(II) 4,4-diaminodiphenylsulphone have been synthesized. Copper salts of counter ion (sulphate, nitrate, chloride) and different reaction media (solvents) were used for theExpand
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