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Control of primordial follicle recruitment by anti-Müllerian hormone in the mouse ovary.
The dimeric glycoprotein anti-Müllerian hormone (AMH) is a member of the transforming growth factor-beta superfamily of growth and differentiation factors. During male fetal sex differentiation, AMHExpand
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Anti-müllerian hormone and anti-müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced
During fetal development, anti-müllerian hormone (AMH) is produced only by Sertoli cells, but postnatally, granulosa cells also produce this peptide growth/differentiation factor. We recentlyExpand
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Anti-Müllerian hormone inhibits initiation of primordial follicle growth in the mouse ovary.
Recruitment of primordial follicles is essential for female fertility; however, the exact mechanisms regulating this process are largely unknown. Earlier studies using anti-Müllerian hormoneExpand
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RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation
In somatic cells of female placental mammals, one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes. Random X chromosome inactivation (XCI) in the embryo is aExpand
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Silencing of Unpaired Chromatin and Histone H2A Ubiquitination in Mammalian Meiosis
ABSTRACT During meiotic prophase in male mammals, the X and Y chromosomes are incorporated in the XY body. This heterochromatic body is transcriptionally silenced and marked by increasedExpand
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Anti-Müllerian Hormone Attenuates the Effects of FSH on Follicle Development in the Mouse Ovary.
Although ovarian follicle growth is under the influence of many growth factors and hormones of which FSH remains one of the most prominent regulators. Therefore, factors affecting the sensitivity ofExpand
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RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation
Evolution of the mammalian sex chromosomes has resulted in a heterologous X and Y pair, where the Y chromosome has lost most of its genes. Hence, there is a need for X-linked gene dosage compensationExpand
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Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation.
Previous studies from this laboratory have described that LNCaP prostate tumor cells contain an androgen receptor (AR) with a point mutation in the steroid-binding domain (codon 868, Thr to Ala).Expand
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Anti-Müllerian hormone attenuates the effects of FSH on follicle development in the mouse ovary.
Although ovarian follicle growth is under the influence of many growth factors and hormones of which FSH remains one of the most prominent regulators. Therefore, factors affecting the sensitivity ofExpand
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RNF12 Activates Xist and Is Essential for X Chromosome Inactivation
In somatic cells of female placental mammals, one of the two X chromosomes is transcriptionally silenced to accomplish an equal dose of X-encoded gene products in males and females. Initiation ofExpand
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