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Effects of nicotinic acid on human fibroblast purine biosynthesis.
- J. A. Boyle, K. Raivio, M. Becker, J. Seegmiller
- Chemistry, Medicine
- Biochimica et biophysica acta
- 10 May 1972
Abstract In fibroblasts derived from normal individuals and from patients with the Lesch—Nyhan syndrome (severe hypoxanthine—guanine phosphoribosyltransferase deficiency), the pyridine nucleotide… Expand
Substrate Stabilization: Genetically Controlled Reciprocal Relationship of Two Human Enzymes
5-Phosphoribosyl-l-pyrophosphate, a substrate shared by adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase, accumulates in human erythrocytes lacking… Expand
Serial studies of the renal clearance of urate and inulin during pregnancy and after the puerperium in normal women.
1. A serial study of renal clearance of urate and inulin was made in thirteen normal women in early, mid and late pregnancy and 6–15 weeks after delivery. 2. The mean serum urate concentration was… Expand
Identification and Quantitation of Ellagic Acid in Muscadine Grape Juice
Muscadine grape juice will occasionally produce a sediment upon standing for long time periods. In order to seek approaches to elimination of this sediment, it was necessary first to identify it and… Expand
Genghis Khan : The History of the World Conqueror
This astonishing book, which is unquestionably the best and most authoritative account of one of the most important events in the world's history, namely the sudden rise and expansion of the Mongol… Expand